The Biomechanic Quality of Dura Mater Correlating Histology 3D-Findings and Rewiev of Melvin Study

Purpose: The work goals are determination of the dural quality of the skull base area under localisation and there are into anterior skull base fossa, which the most connected with paranasal spaces, The method of histology of dural sheats into 3 mutually perpendicular coordinate axis, finding out their biomechanic characteristics and correlation with Melvin and cooworkers study from 1975y.

Results: In literature there is only one study of biomechanic quality of dura mater – Melvin 1974.. Melvin described the technic of study in different plane, but in paper published only one number of biomechanic quality (6–8.103 psi = 0,414- 0,552.106N/m2). The Melvin biomechanic of quality of dura mater was used in all of biomechanic model of study traumatic attack, modelating of different intractranial problem later. In the different part of intracranium the dura mater analyses different biomechanical characteristic. On the convexity and anterior fossa the dura mater have different biomechanical characteristics in coronal and sagital way. (Young modulus - N/m3 0.109- convexity: coronal 0,241, sagital 0,208, anterior skull base fossa: coronal 0,576, sagital 0,410 -(p < 0,1), posterior skull base fossa: coronal 0,229, sagital 0,227, middle fossa: 0,536, median part of skull base 0,563; volume modulus elasticity - N/m3 0.109 – convexity: coronal 0,269, sagital 0,214 (p < 0,1), anterior skull base fossa: coronal 0,89, sagital 0,109 - (p < 0,1), posterior skull base fossa: coronal 0,21, sagital 0,26, middle fossa: 0,152, median part of skull base 0,22). (the convexity dura mater in the direct of coronal way, the anterior skull base fossa in the direct of sagital way dura mater is more tenacious, more resistant). The cribriform plate and midle part of skull base – clival and apical pyramidal dura mater is very thin and have low biomechanical characteristics. The best biomechanical characteristic have convexital dura mater, posterior fossa, falx and tentorium.In the study we have in sagital and coronal plane on convexity and anterior skull base 2 different biomechanical quality – statistically important. This biomechanical study is in correlation of histolotogical study of space collagen distribuction.

Conclusion: The dura on convexity is the strongest and the most stiff, firm cover of brain, to the skull base way comes to this thin, is finner-grained, less strong and less stiff. On convextiy there is dura 2time strong, less elastic then on skull base. The different quality are into coronary nad sagitally plane in convexity (it is statistically significant diference) and to in anterior skull base fossa. Sagitally is dury stronger, less elastic, less drawable on convextiy and anterior skull base fossa. The comparison of 3D histology findings and biomechanic characteristics of dura are very narrow related and correlated. The biomechanical study during tensile test indicate to inner structure of material. The dura mater on skull base form the barrier intracranial and extracranial parts, which is thresholdly strong and form protection for crossway structures (vessels and nerves) through skull base with special arrangement surround their, to preserve separation intracranial space from surround. The dura has functional points (hemodynamic, thermodynamic, liquorodynamic, imnunological, electromagnetic continnuum), but mechanical point of brain protection too.