Planta Med 2016; 82 - PC58
DOI: 10.1055/s-0036-1578760

A Rare Sesquiterpenoid Isolated From Psidium Guajava L.

W Ouyang 1, 3, W Liu 1, L Su 1, S Ye 1, Y Ji 1, T Wang 1, T Gan 1, Y Cao 2
  • 1School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, P. R. China
  • 2College of Food Science, South China Agricultural University, Guangzhou 510642, P. R. China
  • 3National Center for Natural Products Research, University of Mississippi, MS 38677, USA

Psidium guajava L. is widely used as a folk medicine and different parts of this plant have been reported to have many pharmacological properties. A further chemical investigation of this plant, collected in Guangdong province, yielded one sesquiterpenoid (1) by repeated silica gel chromatography. The structure was elucidated on the basis of extensive analysis of spectroscopic data including 1D and 2D NMR. It was concluded that this rare chemical skeleton was the first isolated from natural products [1].

Fig. 1

Acknowledgements: This research was financially supported by the National Natural Science Foundation of China (31201321) and the Education Department of Hunan Province (B13084). Support for Wen Ouyang and Wenlong Liu from the China Scholarship Council is gratefully acknowledged.

References: [1] Colado I. G., Hanson J. R., et al. (1999) Tetrahedron Letters, 40: 6497 – 6498.