Planta Med 2016; 82 - PC57
DOI: 10.1055/s-0036-1578759

Chemical Constituents From Kigelia Africana

A Galal Osman 1, Z Ali 1, IA Khan 1, 2
  • 1National Center For Natural Products Research, National Center for Natural Products Research
  • 2Division of Pharmacognosy, Department of Biomolecular Sciences, School of Pharmacy, University of Mississippi, University, MS, 38677, USA

Kigelia Africana (Lam.) Benth. syn. Kigelia pinnata (Jacq.) D.C. or sausage tree belongs to the family Bignoniaceae and is endemic to different regions in Africa. In traditional medicine, it is prescribed for treatment of microbial infections and skin cancer [1]. Additionally, it possesses curative properties in psoriasis, eczema, ulcers, and rheumatism [2, 3]. From the fruit of this tree, nine iridoid glucosides and phenylpropanoids have been isolated and their structures were determined by detailed 1D and 2D NMR analysis. Compounds 1-3 were found to be isolated for the first time from K. Africana.

Fig. 1

Acknowledgements: This research is supported in part by “Science Based Authentication of Dietary Supplements” funded by the Food and Drug Administration grant number 1U01FD004246 – 05.

References: [1] Houghton PJ, et al. (2000) S. AFR. J. BOT., 68: 14 – 20. [2] Carey, WM, et al. (2008) Pharmacologyonline, 2: 234 – 245. [3] Picerno, P, et al. (2005)J. Nat. Prod., 68: 1610 – 1614.