Thorac Cardiovasc Surg 2017; 65(02): 077-084
DOI: 10.1055/s-0036-1572436
Review Article
Georg Thieme Verlag KG Stuttgart · New York

German Registry for Acute Aortic Dissection Type A: Structure, Results, and Future Perspectives

A. Boening
1   Department of Cardiovascular Surgery, University Hospital Giessen, Giessen, Germany
,
M. Karck
2   Department of Cardiac Surgery, Heidelberg University, Heidelberg, Germany
,
L.O. Conzelmann
3   Department of Cardiac Surgery, Helios Klinik, Karlsruhe, Germany
,
J. Easo
4   Department of Cardiac Surgery, Oldenburg University Hospital, Oldenburg, Germany
,
T. Krüger
5   Department of Thoracic and Cardiovascular Surgery, University Hospital Tübingen, Tübingen, Germany
,
B. Rylski
6   Department of Cardiovascular Surgery, University Hospital Freiburg, Freiburg, Germany
,
E. Weigang
7   Department of Vascular Surgery, Vascular Center Berlin-Brandenburg, Academic Hospital Hubertus, Berlin, Germany
› Author Affiliations
Further Information

Publication History

13 July 2015

30 December 2015

Publication Date:
14 March 2016 (online)

Abstract

The German Registry for Acute Aortic Dissection Type A (GERAADA) as an international registry for acute aortic dissection type A (AADA) offers a unique opportunity to answer questions regarding acute dissections that cannot be answered by single institution's database alone. GERAADA was started in 2006 by the German Society for Thoracic and Cardiovascular Surgery (GSTCVS) and has collected more than 3,300 AADA patients' data from 56 centers in Germany, Austria, and Switzerland up to now. In the second generated validated dataset comprising the years from 2006 to 2010, 2,137 patients were surgically treated for AADA with an overall 30-day mortality of 16.9%, and a new postoperative neurologic dysfunction of 9.5%. Risk factors for neurologic dysfunction were malperfusion syndromes, dissections of the supra-aortic vessels, and longer operating time. Neuroprotective drugs had no influence on stroke rates. Hypothermic circulatory arrest and antegrade selective cerebral perfusion (ACP) led to similar results if arrest times were less than 30 minutes while ACP for longer arrest periods is advisable. Septuagenarians had an early mortality rate (15.8%) similar to the whole cohort's, but the mortality rate in octogenarians (34.9%) was much higher. GERAADA with its validated 2,137 patient files (2006–2010) is the largest database on AADA worldwide and continues to collect data. Structured follow-up of more than 5 years will be available in the future.

Note

Centers participating in GERAADA:


1. Herzzentrum Universität Leipzig, Klinik für Herzchirurgie, Leipzig, Germany


2. Johann Wolfgang-Goethe-Universität / Zentrum der Chirurgie, Klinik für Thorax-, Herz- und thorakale Gefäßchirurgie, Frankfurt am Main, Germany


3. Universitäres Herzzentrum Hamburg / Klinik und Poliklinik für Herz- und Gefäßchirurgie, Hamburg, Germany


4. Universitätsklinikum Tübingen, Klinik für Thorax-, Herz- und Gefäßchirurgie, Tübingen, Germany


5. Ludwig-Maximilians-Universität München, Herzchirurgische Klinik und Poliklinik, München, Germany


6. Universitätsklinikum und Medizinische Fakultät Heidelberg, Klinik für Herzchirurgie, Heidelberg,Germany


7. Klinikum Augsburg, Augsburg, Germany


8. Universitäts-Herzzentrum Freiburg – Bad Krozingen / Standort Freiburg, Klinik für Herz- und Gefäßchirurgie, Freiburg, Germany


9. Johannes-Gutenberg-Universität, Klinik und Poliklinik für HTG-Chirurgie, Mainz, Germany


10. Schüchtermann-Klinik, Herzchirurgie, Bad Rothenfelde, Germany


11. Klinikum Oldenburg gGmbH, Klinik für Herzchirurgie, Oldenburg, Germany


12. Städtisches Klinikum Braunschweig, Klinik für Herz-, Thorax- und Gefässchirurgie, Braunschweig, Germany


13. Universitätsklinikum Ulm, Klinik für Herzchirurgie, Ulm, Germany


14. Rheinische Friedrich-Wilhelms-Universität Bonn, Klinik und Poliklinik für Herzchirurgie, Bonn, Germany


15. Universitätsklinikum Schleswig-Holstein / Campus Lübeck, Klinik für Herzchirurgie, Lübeck,Germany


16. Westdeutsches Herzzentrum Essen / Universitätsklinikum Essen, Klinik für Thorax und Kardiovaskuläre Chirurgie, Essen, Germany


17. Herz- und Gefäß-Klinik GmbH, Klinik für Kardiochirurgie, Bad Neustadt/S., Germany


18. Inselspital, Universitätsklinik für Herz- und Gefässchirurgie, Bern, Switzerland


19. Klinik und Poliklinik für Thorax-, Herz- und Thorakale Gefäßchirurgie, Würzburg, Germany


20. Klinikum Kassel, Klinik für Herz-, Thorax- und Gefäßchirurgie, Kassel, Germany


21. AKH Wien, Universitätsklinik für Chirurgie, Abteilung für Herz- und Thoraxchirurgie, Wien, Austria


22. Klinikum Nürnberg Süd, Klinik für Herzchirurgie, Nürnberg, Germany


23. Universitäts-Herzzentrum Freiburg – Bad Krozingen / Standort Bad Krozingen, Klinik für Herz- und Gefäßchirurgie, Bad Krozingen, Germany


24. Klinikum der Universität zu Köln, Klinik und Poliklinik für Herz- und Thoraxchirurgie, Köln, Germany


25. Kerckhoff-Klinik GmbH, Abteilung für Herz- und Thoraxchirurgie, Bad Nauheim, Germany


26. HELIOS Klinikum Wuppertal / Herzzentrum Wuppertal, Klinik für Herz- und Thoraxchirurgie, Wuppertal, Germany


27. Stadtspital Triemli, Herzchirurgie, Zürich, Switzerland


28. Herzzentrum Dresden GmbH, Klinik für Herzchirurgie, Dresden, Germany


29. Universitätsklinikum Gießen und Marburg / Standort Gießen / Zentrum für Chirurgie, Klinik für Herz-, Kinderherz- und Gefäßchirurgie, Gießen, Germany


30. Klinikum Passau, Passau, Germany


31. Universitätsklinikum Münster, Department für Herz- und Thoraxchirurgie, Klinik für Herzchirurgie, Münster, Germany


32. Evangelisches Klinikum Niederrhein / Herzzentrum Duisburg, Klinik für Herz- und Gefäßchirurgie, Duisburg, Germany


33. Universitätsklinikum des Saarlandes, Klinik für Thorax- und Herz-Gefäßchirurgie, Homburg/Saar, Germany


34. MediClin Herzzentrum Lahr/Baden, Klinik für Herz-, Thorax- und Gefäßchirurgie, Lahr, Germany


35. Albertinen-Krankenhaus, Abteilung für Kardiochirurgie, Hamburg, Germany


36. Herz- und Gefäßzentrum Bad Bevensen, Klinik für Herz-Thorax-Chirurgie, Bad Bevensen, Germany


37. Universitätsklinikum Jena, Klinik für Herzchirurgie und Thoraxchirurgie, Jena, Germany


38. Herz- und Diabeteszentrum NRW, Klinik für Thorax- und Kardiovaskularchirurgie, Bad Oeynhausen,Germany


39. Universitätsklinikum Schleswig-Holstein / Campus Kiel, Klinik für Herz- und Gefäßchirurgie, Kiel, Germany


40. Universitätsklinikum Aachen / RWTH / Campus, Klinik für Thorax-, Herz und Gefäßchirurgie, Aachen, Germany


41. Bundeswehrzentralkrankenhaus, Herz- und Gefäßchirurgie, Koblenz, Germany


42. HELIOS Klinik für Herzchirurgie Karlsruhe, Karlsruhe, Germany


43. Medizinische Universtiät Innsbruck, Universitätsklinik für Visceral-, Transplantations- und Thoraxchirurgie, Innsbruck, Austria


44. Schön Klinik, Klinik für Herzchirurgie, Vogtareuth, Germany


45. Universitätsklinikum Gießen und Marburg / Standort Marburg, Klinik für Herz- und thorakale Gefäßchirurgie, Marburg, Germany


46. Universität Rostock / Medizinische Fakultät, Klinik und Poliklinik für Herzchirurgie, Rostock,Germany


47. Westpfalz-Klinikum GmbH, Thorax-, Herz- und Gefäßchirurgische Klinik, Kaiserslautern, Germany


48. Robert-Bosch-Krankenhaus, Abteilung Herz- und Gefäßchirurgie, Stuttgart, Germany


49. Klinikum Fulda gAG, Klinik für Herz- und Thoraxchirurgie, Fulda, Germany


50. Herz-Zentrum Coswig, Herz-, Gefäß- und Thoraxchirurgie, Coswig, Germany


51. Zentralklinik Bad Berka, Klinik für Herzchirurgie, Bad Berka, Germany


52. Medizinische Hochschule Hannover, Klinik für Herz-, Thorax-, Transplantations- und Gefäßchirurgie, Hannover, Germany


53. Universitätsklinikum Halle (Saale), Universitätsklinik und Poliklinik für Herzchirurgie, Halle (Saale), Germany


54. Sana Herzchirurgie Stuttgart GmbH, Stuttgart, Germany


55. Berufsgenossenschaftliche Kliniken Bergmannsheil / Universitätsklinik, Klinik für Herz- und Thoraxchirurgie, Bochum, Germany


56. Klinikum Links der Weser, Klinik für Thorax-,Herz- und Gefäßchirurgie, Bremen, Germany


 
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