J Neurol Surg Rep 2016; 77(01): e50-e55
DOI: 10.1055/s-0035-1570388
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Nanofibrous Synthetic Dural Patch for Skull Base Defects: Preliminary Experience for Reconstruction after Extended Endonasal Approaches

Francesco Zenga
1  Division of Neurosurgery, Department of Neuroscience, University of Torino, Turin, Italy
,
Valentina Tardivo
1  Division of Neurosurgery, Department of Neuroscience, University of Torino, Turin, Italy
,
Paolo Pacca
1  Division of Neurosurgery, Department of Neuroscience, University of Torino, Turin, Italy
,
Massimiliano Garzaro
2  1st Division of ENT, Department of Surgical Sciences, University of Torino, Turin, Italy
,
Diego Garbossa
1  Division of Neurosurgery, Department of Neuroscience, University of Torino, Turin, Italy
,
Alessandro Ducati
1  Division of Neurosurgery, Department of Neuroscience, University of Torino, Turin, Italy
› Author Affiliations
Further Information

Publication History

29 March 2015

07 November 2015

Publication Date:
01 March 2016 (online)

Abstract

Setting One of the consequences of the widespread use of endoscopic endonasal approaches (EEA) to skull base pathologies is the management of complex skull base defects. Nowadays, the gold standard is a multilayer closure that reproduces the physiological tissue barriers. Several techniques have been described in the literature; however, skull base reconstruction after EEA still represents a matter of debate, especially after extended EEA. A watertight closure is paramount to prevent cerebrospinal fluid leak and meningitis.

Design Regarding this issue, we present our experience with a new synthetic dural patch, ReDura (Medprin Biotech, La Mirada, California, United States), as a subdural inlay in three patients who underwent endoscopic endonasal removal of sellar and suprasellar lesions.

Conclusions ReDura patch showed the same versatility of autologous iliotibial tract. A dural patch that easily adapts to all defects, revealed to be a useful tool for performing watertight closure, possibly in a short operative time, after endoscopic approaches.