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DOI: 10.1055/s-0035-1566401
Use of the Direct Electrostimulation in the Prevention of Motor Deficit in Surgical Treatment of Glioblastoma Multiforme Tumors Localized in the Motor Zone of the Brain
Introduction Glioblastoma multiforme localized in the motor area is the surgical challenge because of the need for more radical resection to extend the life of the patient, and the other due to the risk that radicalism could lead to additional-crippling neurological deficit.
Material and Methods We present a series of 26 patients with glioblastoma multiforme localized in and around the motor area in front of the central sulcus who were hospitalized from October 2004 to February 2009. During all operations, we conducted cortical electrostimulation on displayed area of the brain, to the anatomical location of M1 segment of the motor cortex.
Results Distance of the central sulcus in relation to the coronary suture, measured by magnetic resonance imaging (MRI), was 18.38 mm ± 9.564 mm. The volume of electricity required for a motor response was 9.26 ± 1.286 mA (min.: 7 mA, max.: 11 mA), with increasing distance from the coronary suture the amperage required to explicit motor responses decreased (p < 0.01).
Conclusion The method of direct cerebral cortex electrostimulation is simple and safe method and a binding protocol to the patient's safe operation glioblastoma multiforme localized in the motor area of the brain.
Keywords glioblastoma multiforme; motor area; direct electrostimulation