Planta Med 2015; 81 - PM_163
DOI: 10.1055/s-0035-1565540

Quantitative determination of flavonoids in Centaurea kurdica

P Değirmenci 1, BS Tüzün 1, T Erdoğan 1, B Kıvçak 1
  • 1Ege University, Faculty of Pharmacy, Pharmacognosy Department, Izmir, Turkey

The Asteraceae family is one of the richest vascular plant families in the world with 1600 – 1700 genera and 24000 – 30000 species. Centaurea genus is represented with 192 taxa in Turkey, 114 of which are endemic. Many species of the genus Centaurea have traditionally been used for their antibacterial, antirheumatic, diuretic, stomachic, astringent, choleretic, cytotoxic, antipyretic and tonic properties [1,2].

In this study, Centaurea kurdica was collected from Elazig, Turkey. It was identified by Ugur Cakilcioglu, Department of Plant and Animal Production, Tunceli University. The herbarium of the plant is deposited in Ege University Faculty of Pharmacy, Department of Pharmacognosy (Herbarium no:1457). The chloroform, methanol:water (1:1) and n-hexane extracts of the aerial parts were prepared. According to the previous studies, the chloroform extract has more terpenoids and flavonoids than the other extracts [3,4]. The presence of hesperidin, naringin, eupatorin, quercetin dihydrate and chrysin was analyzed using LC-MS method. In the present study, the amount of the eupatorin was found as 1.4% in the chloroform extract. The amount of eupatorin was calculated by using the equation y = 20635.1+9985.84*x (R2= 0.9998). This compound was detected for the first time from this plant by LC-MS.

References:

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