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J Pediatr Genet 2015; 04(04): 199-200
DOI: 10.1055/s-0035-1565270
Case Report
Georg Thieme Verlag KG Stuttgart · New York

A New Case of a Complex Small Supernumerary Marker Chromosome: A Der(9)t(7;9)(p22;q22) due to a Maternal Balanced Rearrangement

Marine Manvelyan
1   Jena University Hospital, Friedrich Schiller University, Institute of Human Genetics, Jena, Germany
2   Research Center of Maternal and Child Health Protection, Yerevan, Armenia
,
Izabella Simonyan
2   Research Center of Maternal and Child Health Protection, Yerevan, Armenia
,
Galina Hovhannisyan
3   Department of Genetics and Cytology, Yerevan State University, Yerevan, Armenia
,
Rouben Aroutiounian
3   Department of Genetics and Cytology, Yerevan State University, Yerevan, Armenia
,
Ahmed B. Hamid
1   Jena University Hospital, Friedrich Schiller University, Institute of Human Genetics, Jena, Germany
,
Thomas Liehr
1   Jena University Hospital, Friedrich Schiller University, Institute of Human Genetics, Jena, Germany
› Author Affiliations
Further Information

Publication History

22 April 2015

28 April 2015

Publication Date:
20 October 2015 (online)

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Abstract

Complex small supernumerary marker chromosomes (sSMCs) constitute one of the smallest subsets within the patients with an sSMC. Complex sSMCs consist of chromosomal material derived from more than one chromosome, for example, the derivative der(22)t(11;22)(q23;q11.2) in Emanuel syndrome. Here, a yet unreported case of a complex sSMC formed due to a t(7;9)(p22;q22)mat is presented.

Keywords

complex small supernumerary marker chromosomes (sSMCs) - genotype-phenotype correlation - partial trisomy 9 - partial trisomy 7
 

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