Int J Sports Med 2016; 37(05): 347-353
DOI: 10.1055/s-0035-1565202
Physiology & Biochemistry
© Georg Thieme Verlag KG Stuttgart · New York

Effects of Wearing Compression Stockings on the Physical Performance of T2DM Men with MetS

C. Brinkmann
1   Department of Molecular and Cellular Sport Medicine, Institute of Cardiovascular Research and Sport Medicine, German Sport University Cologne, Cologne, Germany
,
R. Hermann
2   Institute of Movement and Neurosciences, German Sport University Cologne, Cologne, Germany
,
E. Rühl
2   Institute of Movement and Neurosciences, German Sport University Cologne, Cologne, Germany
,
H. Kerzel
1   Department of Molecular and Cellular Sport Medicine, Institute of Cardiovascular Research and Sport Medicine, German Sport University Cologne, Cologne, Germany
,
L. Reinhardt
1   Department of Molecular and Cellular Sport Medicine, Institute of Cardiovascular Research and Sport Medicine, German Sport University Cologne, Cologne, Germany
,
M. Grau
1   Department of Molecular and Cellular Sport Medicine, Institute of Cardiovascular Research and Sport Medicine, German Sport University Cologne, Cologne, Germany
,
J. Latsch
3   Department of Preventive and Rehabilitative Sport Medicine, Institute of Cardiovascular Research and Sport Medicine, German Sport University Cologne, Cologne, Germany
,
M. Kohl-Bareis
4   RheinAhrCampus, University of Applied Sciences Koblenz, Remagen, Germany
,
W. Bloch
1   Department of Molecular and Cellular Sport Medicine, Institute of Cardiovascular Research and Sport Medicine, German Sport University Cologne, Cologne, Germany
,
K. Brixius
1   Department of Molecular and Cellular Sport Medicine, Institute of Cardiovascular Research and Sport Medicine, German Sport University Cologne, Cologne, Germany
› Author Affiliations
Further Information

Publication History



accepted after revision 19 October 2015

Publication Date:
09 February 2016 (online)

Abstract

Metabolic syndrome (MetS) and type 2 diabetes mellitus (T2DM) are associated with macro- and microcirculatory complications that reduce physical performance. Wearing compression garments to potentially optimize hemodynamics has been discussed. This study investigates the effects of wearing compression stockings on physical performance-related variables in type 2 diabetic men with metabolic syndrome (n=9, 57±12 years, BMI: 36±4 kg/m2). Participants served as their own controls in a randomized 3*3 crossover study wearing below-knee stockings with either compression (24 or 30 mmHg ankle pressure) or no compression. Venous pooling and lower limb oxygenation profiles were determined with near-infrared spectroscopy and arterial oxygen saturation was determined using a pulse oxymeter. Measurements were performed in the supine lying position, during standing, following 10 tiptoe exercises and after submaximal intensity cycling. In addition, lactate and erythrocyte deformability were analyzed in capillary blood pre- and post-exercise. Erythrocyte deformability was analyzed using a laser-assisted optical rotational red cell analyzer. No significant differences in any variables when wearing different compression or regular stockings were evident at any point of measurement. This study did not reveal any beneficial effects of wearing compression stockings at rest and during acute bouts of moderately intense exercise in this particular patient group.

Supplementary Material

 
  • References

  • 1 Agu O, Baker D, Seifalian AM. Effect of graduated compression stockings on limb oxygenation and venous function during exercise in patients with venous insufficiency. Vascular 2004; 12: 69-76
  • 2 Alberti KG, Zimmet P, Shaw J. Metabolic syndrome – a new world-wide definition. A consensus statement from the International Diabetes Federation. Diabet Med 2006; 23: 469-480
  • 3 Ali A, Caine MP, Snow BG. Graduated compression stockings: physiological and perceptual responses during and after exercise. J Sports Sci 2007; 25: 413-419
  • 4 Ali A, Creasy RH, Edge JA. Physiological effects of wearing graduated compression stockings during running. Eur J Appl Physiol 2010; 109: 1017-1025
  • 5 Ali A, Creasy RH, Edge JA. The effect of graduated compression stockings on running performance. J Strength Cond Res 2011; 25: 1385-1392
  • 6 Belcaro G, Christopoulos A, Nicolaides AN. Diabetic microangiopathy treated with elastic compression – a microcirculatory evaluation using laser-Doppler flowmetry, transcutaneous PO2/PCO2 and capillary permeability measurements. Vasa 1990; 19: 247-251
  • 7 Belcaro G, Laurora G, Cesarone MR, Pomante P. Elastic stockings in diabetic microangiopathy. Long-term clinical and microcirculatory evaluation. Vasa 1992; 21: 193-197
  • 8 Bizjak D, Brinkmann C, Bloch W, Grau M. Increase in red blood cell-nitric oxide synthase dependent nitric oxide production during red blood cell aging in health and disease: a study on age dependent changes of rheologic and enzymatic properties in red blood cells. Plos One 2015; 10: e0125206
  • 9 Bochmann RP, Seibel W, Haase E, Hietschold V, Rödel H, Deussen A. External compression increases forearm perfusion. J Appl Physiol 2005; 99: 2337-2344
  • 10 Bollinger A, Frey J, Jäger K, Furrer J, Seglias J, Siegenthaler W. Patterns of diffusion through skin capillaries in patients with long-term diabetes. N Engl J Med 1982; 307: 1305-1310
  • 11 Bonadonna RC, Cucinotta D, Fedele D, Riccardi G, Tiengo A. The metabolic syndrome is a risk indicator of microvascular and macrovascular complications in diabetes: results from Metascreen, a multicenter diabetes clinic-based survey. Diabetes Care 2006; 29: 2701-2707
  • 12 Born D, Sperlich B, Holmberg H. Bringing light into the dark: effects of compression clothing on performance and recovery. Int J Sports Physiol Perform 2013; 8: 4-18
  • 13 Bringard A, Denis R, Belluye N, Perrey S. Effects of compression tights on calf muscle oxygenation and venous pooling during quiet resting in supine and standing positions. J Sports Med Phys Fitness 2006; 46: 548-554
  • 14 Chatard JC, Atlaoui D, Farjanel J, Louisy F, Rastel D, Guézennec CY. Elastic stockings, performance and leg pain recovery in 63-year-old sportsmen. Eur J Appl Physiol 2004; 93: 347-352
  • 15 De Blasi RA, Ferrari M, Natali A, Conti G, Mega A, Gasparetto A. Noninvasive measurement of forearm blood flow and oxygen consumption by near-infrared spectroscopy. J Appl Physiol 1994; 76: 1388-1393
  • 16 Ferrari M, Muthalib M, Quaresima V. The use of near-infrared spectroscopy in understanding skeletal muscle physiology: recent developments. Philos Trans A Math Phys Eng Sci 2011; 369: 4577-4590
  • 17 Hällsten K, Yki-Järvinen H, Peltoniemi P, Oikonen V, Takala T, Kemppainen J, Laine H, Bergman J, Bolli GB, Knuuti J, Nuutila P. Insulin- and exercise-stimulated skeletal muscle blood flow and glucose uptake in obese men. Obes Res 2003; 11: 257-265
  • 18 Hardeman MR, Dobbe JG, Ince C. The Laser-assisted Optical Rotational Cell Analyzer (LORCA) as red blood cell aggregometer. Clin Hemorheol Microcirc 2001; 25: 1-11
  • 19 Harriss DJ, Atkinson G. Ethical standards in sport and exercise science research: 2014 update. Int J Sports Med 2013; 34: 1025-1028
  • 20 Hegarty-Craver M, Kwon C, Oxenham W, Grant E, Reid L. Towards characterizing the pressure profiles of medical compression hosiery: an investigation of current measurement devices and techniques. J Text Inst 2015; 106: 757-767
  • 21 Jansson PA, Gudbjörnsdottir HS, Andersson OK, Lönnroth PN. The effect of metformin on adipose tissue metabolism and peripheral blood flow in subjects with NIDDM. Diabetes Care 1996; 19: 160-164
  • 22 Jonker MJ, de Boer EM, Adèr HJ, Bezemer PD. The oedema-protective effect of Lycra support stockings. Dermatology 2001; 203: 294-298
  • 23 Kemmler W, Stengel von S, Köckritz C, Mayhew J, Wassermann A, Zapf J. Effect of compression stockings on running performance in men runners. J Strength Cond Res 2009; 23: 101-105
  • 24 Lawrence D, Kakkar VV. Graduated, static, external compression of the lower limb: a physiological assessment. The Br J Surg 1980; 67: 119-121
  • 25 Mani R, Yarde S, Edmonds M. Prevalence of deep venous incompetence and microvascular abnormalities in patients with diabetes mellitus. Int J Low Extreme Wounds 2011; 10: 75-79
  • 26 Miossec P, Zkhiri F, Paries J, David-Dufilho M, Devynck MA, Valensi PE. Effect of pravastatin on erythrocyte rheological and biochemical properties in poorly controlled type 2 diabetic patients. Diab Med 1999; 16: 424-430
  • 27 Rimaud D, Messonnier L, Castells J, Devillard X, Calmels P. Effects of compression stockings during exercise and recovery on blood lactate kinetics. Eur J Appl Physiol 2010; 110: 425-433
  • 28 Schofield I, Malik R, Izzard A, Austin C, Heagerty A. Vascular structural and functional changes in type 2 diabetes mellitus: evidence for the roles of abnormal myogenic responsiveness and dyslipidemia. Circulation 2002; 106: 3037-3043
  • 29 Wahl P, Bloch W, Mester J, Born D, Sperlich B. Effects of different levels of compression during sub-maximal and high-intensity exercise on erythrocyte deformability. Eur J Appl Physiol 2012; 112: 2163-2169
  • 30 Wiernsperger N, Nivoit P, De Aguiar LG, Kraemer Bouskela E. Microcirculation and the metabolic syndrome. Microcirculation 2007; 14: 403-438
  • 31 Willenberg T, Schumacher A, Amann-Vesti B, Jacomella V, Thalhammer C, Diehm N, Baumgartner I, Husmann M. Impact of obesity on venous hemodynamics of the lower limbs. J Vasc Surg 2010; 52: 664-668