Int J Angiol 2016; 25(02): 099-103
DOI: 10.1055/s-0035-1563606
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Vascular Complications Associated with Transfemoral Aortic Valve Replacement

George L. Hines
1   Department of Thoracic and Cardiovascular Surgery, Winthrop University Hospital, Mineola, New York
Vita Jaspan
1   Department of Thoracic and Cardiovascular Surgery, Winthrop University Hospital, Mineola, New York
Brian J. Kelly
2   Department of Surgery, SUNY-Stony Brook, Stony Brook, New York
Rose Calixte
3   Department of Biostatistics, Winthrop University Hospital, Mineola, New York
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07. September 2015 (online)


Background Transfemoral aortic valve replacement (TAVR) is a novel technique for treating aortic stenosis, yet vascular complications are yet to be delineated.

Objectives This study aims to study the vascular complications of TAVR with Edwards Sapien valves (Edwards Lifesciences Corp., Irvine, CA).

Methods We performed a retrospective evaluation of TAVR patients. Standard demographics, femoral vessel and sheath size, access type (femoral cut-down [FC], percutaneous access [PFA], and iliac conduit [IC]), and treatment method were recorded. Complications were defined by the Valve Academic Research Consortium Criteria. Logistic regression was used for statistical analysis.

Results A total of 99 patients underwent TAVR between February 15, 2012 and July 17, 2013 with an Edwards Sapien valve. Out of which, 48 were males with a mean age of 83 ± 7 years. Overall, 33 had FC, 58 had PFA, and 6 had an IC. A total of 17 major (2 aortic and 15 iliac) and 38 minor complications (36 access and 2 emboli) occurred. Aortic complications were managed by open repair (OR, 1) or percutaneous repair (PR, 1). Overall, 12 iliac injuries were managed by PR and 3 by OR. Out of the 33 groin complications in FC patients 8 (24%) were treated by OR, whereas 30 (52%) of the 58 groin complications in PTA patients were treated by PR. There were no differences in transfusion requirements or length of stay.

Conclusion Vascular complications of TAVR are common with most being minor, related to access site and causing no immediate sequelae. Iliac injury can be managed by PR or OR. Aortic injury is associated with significant mortality. These findings increase vascular surgeons' awareness of these complications and how to manage them.