Synthesis 2016; 48(04): 504-511
DOI: 10.1055/s-0035-1560397
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© Georg Thieme Verlag Stuttgart · New York

Copper-Catalyzed Negishi Coupling of Diarylzinc Reagents with Aryl Iodides

Surendra Thapa
Department of Chemistry & Chemical Biology, The University of New Mexico, Albuquerque, NM 87131, USA   Email: rgiri@unm.edu
,
Adarsh S. Vangala
Department of Chemistry & Chemical Biology, The University of New Mexico, Albuquerque, NM 87131, USA   Email: rgiri@unm.edu
,
Ramesh Giri*
Department of Chemistry & Chemical Biology, The University of New Mexico, Albuquerque, NM 87131, USA   Email: rgiri@unm.edu
› Author Affiliations
Further Information

Publication History

Received: 04 October 2015

Accepted after revision: 04 November 2015

Publication Date:
04 January 2016 (eFirst)

Abstract

We report an efficient copper(I) iodide catalyzed cross-coupling­ of diarylzinc reagents with aryl iodides. The reaction proceeds under ligand-free conditions at low catalyst loading (5 mol%) and tolerates a variety of functional groups.

Supporting Information

 
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