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J Neurol Surg A Cent Eur Neurosurg 2016; 77(04): 297-299
DOI: 10.1055/s-0035-1559810
Original Article
Georg Thieme Verlag KG Stuttgart · New York

Acellular Dermal Matrix Combined with Autologous Skin Grafts for Closure of Chronic Wounds after Reconstruction of Skull Defects with Titanium Mesh

Xu Luo
1   Department of Wounds and Burns Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China
,
Cai Lin
2   Department of Burn, The First Affiliated Hospital of Wenzhou Medical College, Wenzhou, Zhejiang Province, China
,
Xinling Wang
3   Department of Outpatient Services Center, The Taihe Hospital of Hubei Medical College, Shiyan, HuBei Province, China
,
Xiangwei Lin
1   Department of Wounds and Burns Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China
,
Sunyue He
4   Department of Clinical Medical Sciences, The School of Wenzhou Medical University, Wenzhou, Zhejiang Province, China
,
Yunfeng Liu
1   Department of Wounds and Burns Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China
,
Yong Zhang
1   Department of Wounds and Burns Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China
,
Ruijin Yang
1   Department of Wounds and Burns Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China
,
Xinguo Zhu
5   Department of General Surgery, The First Affiliated Hospital of Suzhou Medical College, Suzhou Province, China
› Author Affiliations
Further Information

Publication History

20 November 2014

24 April 2015

Publication Date:
18 April 2016 (online)

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Abstract

Objective The closure of chronic wounds after skull defect reconstruction with titanium mesh is one of the most challenging problems for plastic and reconstructive surgeons. Current approaches are disappointing.

Methods In 10 patients, we explored the role of acellular dermal matrix (ADM) in combination with autologous skin grafts (ASGs) for closure of chronic wounds after skull reconstruction with titanium.

Results ADM and ASG survived in all patients. Grade A healing (healing well without defect) was achieved. The average operating time was 30 to 45 minutes, and the average blood loss 30 to 50 mL. After 3 months, the wound was still closed in all patients.

Conclusion The combination of ADM plus ASG obtained a high wound closure rate. ADM plus ASG allows avoiding other procedures such as rotational flaps and free flaps that require more operating time, special equipment, and adequate training.

Keywords

titanium mesh - acellular dermal matrix - cranial
 

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