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Indian Journal of Neurosurgery 2015; 04(02): 114-116
DOI: 10.1055/s-0035-1558964
Illustrated Case Review
Neurological Surgeons' Society of India

Transformation of Snow White to Ugly Duckling: Neurobehavioral Impact of Childhood Craniopharyngioma

Suravi Patra
1   Department of Psychiatry, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India
,
Ashok K. Mahapatra
2   Department of Neurosurgery, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India
› Author Affiliations
Further Information

Publication History

06 April 2015

14 May 2015

Publication Date:
28 July 2015 (online)

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Abstract

Neurobehavioral problems are seen in children with craniopharyngiomas both before and after treatment, which cause significant morbidity. Behavioral problems include aggressive behavior, hyperphagia, impaired school performance, and poor social behavior. These children have impairment in psychosocial functioning and have a poor quality of life. Family members face a lot of difficulty in managing these difficulties. These behavioral problems are difficult to manage even by the health-care givers as there are no evidence-based treatment protocols. Behavioral therapy has been documented to be of benefit in certain cases, and the authors here also demonstrate the usefulness of behavior therapy in managing the behavioral problems of a child who had a successful gross total excision of craniopharyngioma with an otherwise uneventful postoperative course.

Keywords

childhood craniopharyngioma - neurobehavioral disorders - management
 

  • References

  • 1 Müller HL. Craniopharyngioma—a childhood and adult disease with challenging characteristics. Front Endocrinol (Lausanne) 2012; 3 (3) 80
    PubMedGoogle Scholar
  • 2 Müller HL. Childhood craniopharyngioma. Pituitary 2013; 16 (1) 56-67
    CrossrefPubMedGoogle Scholar
  • 3 Zada G, Kintz N, Pulido M, Amezcua L. Prevalence of neurobehavioral, social, and emotional dysfunction in patients treated for childhood craniopharyngioma: a systematic literature review. PLoS ONE 2013; 8 (11) e76562
    CrossrefPubMedGoogle Scholar
  • 4 Jain M, Passi GR. Assessment of a modified Mini-Mental Scale for cognitive functions in children. Indian Pediatr 2005; 42 (9) 907-912
    PubMedGoogle Scholar
  • 5 Jellinek MS, Murphy JM, Little M, Pagano ME, Comer DM, Kelleher KJ. Use of the Pediatric Symptom Checklist to screen for psychosocial problems in pediatric primary care: a national feasibility study. Arch Pediatr Adolesc Med 1999; 153 (3) 254-260
    PubMedGoogle Scholar
  • 6 Varni JW, Seid M, Kurtin PS. PedsQL 4.0: reliability and validity of the Pediatric Quality of Life Inventory version 4.0 generic core scales in healthy and patient populations. Med Care 2001; 39 (8) 800-812
    CrossrefPubMedGoogle Scholar
  • 7 Laffond C, Dellatolas G, Alapetite C , et al. Quality-of-life, mood and executive functioning after childhood craniopharyngioma treated with surgery and proton beam therapy. Brain Inj 2012; 26 (3) 270-281
    CrossrefPubMedGoogle Scholar
  • 8 Prusty GK, , Subramanya, Hemalatha V, Narayanan HS. Craniopharyngioma presenting as ‘mania’-case report. Indian J Psychiatry 1982; 24 (3) 305-306
    PubMedGoogle Scholar
  • 9 Dolson EP, Conklin HM, Li C, Xiong X, Merchant TE. Predicting behavioral problems in craniopharyngioma survivors after conformal radiation therapy. Pediatr Blood Cancer 2009; 52 (7) 860-864
    CrossrefPubMedGoogle Scholar
  • 10 Hammond JL, Hall SS. Functional analysis and treatment of aggressive behavior following resection of a craniopharyngioma. Dev Med Child Neurol 2011; 53 (4) 369-374
    CrossrefPubMedGoogle Scholar