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Indian Journal of Neurosurgery 2015; 04(02): 124-127
DOI: 10.1055/s-0035-1558838
Images in Neurosurgery
Neurological Surgeons' Society of India

Atypical Chordoid Glioma of the Third Ventricle: A Case Report

Manash Bora
1   Department of Neurosurgery, SMS Medical College, Jaipur, Rajasthan, India
,
R. S. Mittal
1   Department of Neurosurgery, SMS Medical College, Jaipur, Rajasthan, India
,
Amitesh Dubey
1   Department of Neurosurgery, SMS Medical College, Jaipur, Rajasthan, India
,
S. Singhvi
2   Patho Care and Research Centre, Jaipur, Rajasthan, India
› Author Affiliations
Further Information

Publication History

08 April 2015

14 May 2015

Publication Date:
28 July 2015 (online)

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Abstract

Chordoid glioma of the third ventricle was classified as a rare tumor by the World Health Organization in 2000. Approximately 55 cases have been reported so far in world literature. These tumors are usually slow growing presenting with features of raised ICP. Most tumors have low proliferative index and these tumors are immunohistochemically negative for P53. We are reporting a case of chordoid glioma of the third ventricle, with atypical features of high proliferative index and P53 positivity on immunohistochemistry.

Keywords

chordoid glioma - KI-67 - P53 - third ventricle - immunohistochemistry (IHC)
 

  • References

  • 1 Desouza RM, Bodi I, Thomas N, Marsh H, Crocker M. Chordoid glioma: ten years of a low-grade tumor with high morbidity. Skull Base 2010; 20 (2) 125-138
    Article in Thieme ConnectPubMedGoogle Scholar
  • 2 Pomper MG, Passe TJ, Burger PC, Scheithauer BW, Brat DJ. Chordoid glioma: a neoplasm unique to the hypothalamus and anterior third ventricle. AJNR Am J Neuroradiol 2001; 22 (3) 464-469
    PubMedGoogle Scholar
  • 3 Vajtai I, Varga Z, Scheithauer BW, Bodosi M. Chordoid glioma of the third ventricle: confirmatory report of a new entity. Hum Pathol 1999; 30 (6) 723-726
    CrossrefPubMedGoogle Scholar
  • 4 Reifenberger G, Weber T, Weber RG , et al. Chordoid glioma of the third ventricle: immunohistochemical and molecular genetic characterization of a novel tumor entity. Brain Pathol 1999; 9 (4) 617-626
    CrossrefPubMedGoogle Scholar
  • 5 Wanschitz J, Schmidbauer M, Maier H, Rössler K, Vorkapic P, Budka H. Suprasellar meningioma with expression of glial fibrillary acidic protein: a peculiar variant. Acta Neuropathol 1995; 90 (5) 539-544
    CrossrefPubMedGoogle Scholar
  • 6 Brat DJ, Scheithauer BW, Staugaitis SM, Cortez SC, Brecher K, Burger PC. Third ventricular chordoid glioma: a distinct clinicopathologic entity. J Neuropathol Exp Neurol 1998; 57 (3) 283-290
    CrossrefPubMedGoogle Scholar
  • 7 Brat DJ, Scheithauer BW, Cortez SC, Reifenberger G, Burger PC. Chordoid glioma of the third ventricle. In: Kleihuis P, Cavenee WK. , eds. Pathology and Genetics of Tumours of the Nervous System. 2nd ed. Lyon: International Agency for Research; 2000: 90-91
    Google Scholar
  • 8 Kendall B, Reider-Grosswasser I, Valentine A. Diagnosis of masses presenting within the ventricles on computed tomography. Neuroradiology 1983; 25 (1) 11-22
    CrossrefPubMedGoogle Scholar
  • 9 Osborn AG. Brain tumors and tumor like masses: classification and differential diagnosis. In: Diagnostic Neuroradiology. Mosby; 1994: 399-528
    Google Scholar
  • 10 Sato K, Kubota T, Ishida M, Yoshida K, Takeuchi H, Handa Y. Immunohistochemical and ultrastructural study of chordoid glioma of the third ventricle: its tanycytic differentiation. Acta Neuropathol 2003; 106 (2) 176-180
    CrossrefPubMedGoogle Scholar