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Pharmacopsychiatry 2015; 25 - A1
DOI: 10.1055/s-0035-1557939
DOI: 10.1055/s-0035-1557939
Adverse drug reactions: vascular parkinsonism and sedation – a pharmacokinetic and pharmacodynamic evaluation from the German Pharmacovigilance project AMSP
We present a case of a vascular parkinsonism and severe sedation associated with quetiapine, aripiprazole and valproic acid. The patient was suffering from a bipolar affective disorder. Pharmacokinetic and pharmacodynmic aspects and interaction risks especially in elderly patients were demonstrated. These adverse drug reactions were registrated from the German pharmacovigilance study “Arzneimittelsicherheit in der Psychiatrie”(AMSP).