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Journal of Pediatric Neurology 2008; 06(03): 221-225
DOI: 10.1055/s-0035-1557470
Original Article
Georg Thieme Verlag KG Stuttgart – New York

Single photon emission tomography in children with autism

Pratibha Singhi
a   Department of Pediatrics, Advanced Pediatric Center, Postgraduate Institute of Medical Education & Research, Chandigarh, India
,
Bhagwant R. Mittal
b   Department of Nuclear Medicine, Postgraduate Institute of Medical Education & Research, Chandigarh, India
,
Ravishankar Nagaraj
a   Department of Pediatrics, Advanced Pediatric Center, Postgraduate Institute of Medical Education & Research, Chandigarh, India
,
Prabhjot Malhi
a   Department of Pediatrics, Advanced Pediatric Center, Postgraduate Institute of Medical Education & Research, Chandigarh, India
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Publication History

01 April 2008

08 June 2008

Publication Date:
30 July 2015 (online)

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Abstract

Single photon emission tomography (SPECT) of the brain was studied in 22 children with primary autism with varying degrees of severity. Fifteen children had no perfusion abnormalities on SPECT imaging. Of the remaining seven, decreased perfusion in the left frontoparietal cortex was seen in three, and in the left inferior and medial frontal cortex in two children. No correlation could be found between SPECT, electroencephalography, and magnetic resonance imaging findings. Our findings are similar to those previously reported in some studies, and present areas of further inquiry regarding therapeutic intervention or diagnosis.

Keywords

Autism - children - imaging - SPECT