Favorable outcome in a child with bilateral striatal necrosis following measles
13 April 2006
07 June 2006
30 July 2015 (online)
Acute bilateral striatal necrosis is considered to be a rare heterogeneous entity, in view of the variability of its clinical presentation. We report a 4-year-old girl presented with typical clinical features of measles associated with acute bilateral striatal necrosis. The clinical symptoms were an abrupt onset of seizures, hemiplegia, expressive aphasia and extrapyramidal signs on the seventh day of illness. Serum was positive for measles IgG and IgM. Cranial magnetic resonance imaging showed hyperintensities on T2 weighted images affecting the putamen and caudate nuclei bilaterally. Neurologic recovery occurred within six weeks following therapy with corticosteroids. Repeated magnetic resonance imaging in follow up showed significant resolution of the lesions.