J Pediatr Neurol 2006; 04(04): 275-277
DOI: 10.1055/s-0035-1557342
Case Report
Georg Thieme Verlag KG Stuttgart – New York

Favorable outcome in a child with bilateral striatal necrosis following measles

Munni Ray
a  Department of Pediatrics, Advanced Pediatric Centre, Postgraduate Institute of Medical Education and Research, India
,
Kavitha Kothur
a  Department of Pediatrics, Advanced Pediatric Centre, Postgraduate Institute of Medical Education and Research, India
,
Niranjan Khandelwal
b  Department of Radiodiagnosis, Advanced Pediatric Centre, Postgraduate Institute of Medical Education and Research, India
› Author Affiliations

Subject Editor:
Further Information

Publication History

13 April 2006

07 June 2006

Publication Date:
30 July 2015 (online)

Abstract

Acute bilateral striatal necrosis is considered to be a rare heterogeneous entity, in view of the variability of its clinical presentation. We report a 4-year-old girl presented with typical clinical features of measles associated with acute bilateral striatal necrosis. The clinical symptoms were an abrupt onset of seizures, hemiplegia, expressive aphasia and extrapyramidal signs on the seventh day of illness. Serum was positive for measles IgG and IgM. Cranial magnetic resonance imaging showed hyperintensities on T2 weighted images affecting the putamen and caudate nuclei bilaterally. Neurologic recovery occurred within six weeks following therapy with corticosteroids. Repeated magnetic resonance imaging in follow up showed significant resolution of the lesions.