Can Devic Disease Involve Peripheral Nerves?

Abstract

Devic disease (DD) or neuromyelitis optica (NMO) is a rare demyelinating disease of central nervous system in children. It may have monophasic or relapsing course. A diagnosis of DD requires involvement of unilateral or bilateral optic nerves, more than three longitudinal segments of the spinal cord and presence of NMO-immunoglobulin G or antiaquaporin 4 antibody in the serum. It is usually associated with normal cranial magnetic resonance imaging during first episode of DD. Here, we report a case of DD with unusual association of peripheral nerve involvement of the axonal type.

Keywords

neuromyelitis optica - demyelination - peripheral nerve - Devic disease

• References

• 1 Weinshenker BG. Neuromyelitis optica is distinct from multiple sclerosis. Arch Neurol 2007; 64 (6) 899-901
• 2 Noseworthy JH, Lucchinetti C, Rodriguez M, Weinshenker BG. Multiple sclerosis. N Engl J Med 2000; 343 (13) 938-952
• 3 Stephan LH. Multiple sclerosis and other demyelinating disease. In: Isselbacher KJ, Braunwald E, Wilson JD, Martin JB, Fauci AS, Kasper DL, , eds. Harrison's Principles of Internal Medicine. 13th ed. New York: McGraw Hill; 1994: 2291-2355
• 4 Cloys DE, Netsky MG. Neuromyelitis optica. In: Vinken PJ, Bruyn GW, , eds. Handbook of Neurology. Volume 9. Amsterdam: North Holland Publishing Co.; 1970: 426-437
• 5 Mikaeloff Y, Caridade G, Husson B, Suissa S, Tardieu M ; Neuropediatric KIDSEP Study Group of the French Neuropediatric Society Acute disseminated encephalomyelitis cohort study: prognostic factors for relapse. Eur J Paediatr Neurol 2007; 11 (2) 90-95
• 6 Wingerchuk DM, Lennon VA, Pittock SJ, Lucchinetti CF, Weinshenker BG. Revised diagnostic criteria for neuromyelitis optica. Neurology 2006; 66 (10) 1485-1489
• 7 Kantarci OH, Weinshenker BG. Natural history of multiple sclerosis. Neurol Clin 2005; 23 (1) 17-38 , v
• 8 Polman CH, Reingold SC, Edan G , et al. Diagnostic criteria for multiple sclerosis: 2005 revisions to the “McDonald Criteria”. Ann Neurol 2005; 58 (6) 840-846
• 9 Aimoto Y, Ito K, Moriwaka F, Tashiro K, Abe K. Demyelinating peripheral neuropathy in Devic disease. Jpn J Psychiatry Neurol 1991; 45 (4) 861-864
• 10 Warabi Y, Yamazaki M, Shimizu T, Nagao M. Abnormal nerve conduction study findings indicating the existence of peripheral neuropathy in multiple sclerosis and neuromyelitis optica. Biomed Res Int 2013; 2013: 847670