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Planta Med 2015; 81 - PO1
DOI: 10.1055/s-0035-1556333
DOI: 10.1055/s-0035-1556333
HIV inhibitory activity from Papua New Guinean medicinal plants
Papua New Guinea has enormous biological diversity as a result of its topography and tropical latitude. It also has a long and continued use of medicinal plants. In our lab we use bioassay guided discovery and dereplication based on a whole cell HIV assays, p24 flow cytometry, various chromatographic methods, and accurate mass LC/MS/MS. We have explored several collections of medicinal plants gathered by Pharmacy Students under the guidance of UPNG botanists and found several plants with potent anti-HIV activity. Here we report our recent findings on several active plants, including Macaranga Tanarius, Causarina oligodon and Crassocephalum crepidiodes.