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Planta Med 2015; 81 - PE10
DOI: 10.1055/s-0035-1556218
DOI: 10.1055/s-0035-1556218
Antifungal prenylated isoflavonoids from Maclura aurantiaca
Three prenylated isoflavonoids (1 – 3) have been isolated from the ethanolic extract of Maclura aurantiaca fruits. The isolated compounds were chemically identified as 3'-hydroxyeuchrenone (1), euchrenone (2), 5,3',4'-trihydroxy-6-(3-methylbut-2-en-1-yl) isoflavone (3). Compounds 1 and 2 showed antifungal activities against Candida glabrata with IC50 values of 5.7 µg/ml and 1.0 µg/ml, respectively. Compound 3 showed antifungal activities against Cryptococcus neofomans and Candida glabrata with IC50 values of 5.0 µg/ml and 4.9 µg/ml, respectively.