Abstract
A 7-year-old male child presented with moderate degree fever, yellowish discoloration of eyes and urine. Examination on admission revealed severe anemia, jaundice, hepatomegaly, and splenomegaly. On the day following admission, the child showed evidence of blackish discoloration of urine. The diagnosis was established as viral A hepatitis with glucose-6-phosphate dehydrogenase (G6PD) deficiency. The child recovered with supportive therapy. We suggest that either universal immunization against hepatitis A, or routine newborn screening for G6PD deficiency, could prevent the serious morbidity or mortality that can occur when these two conditions coexist.
Keywords
hepatitis - G6PD - viral - hemolysis - intravascular