Abstract
Primary intracranial mesenchymal chondrosarcoma is an extremely rare tumor. We present
a case of primary intracranial mesenchymal chondrosarcoma in a young female who presented
with headache, loss of vision, and one episode of convulsions associated with nausea
and vomiting. MRI brain revealed a large, well-marginated, lobulated, partially calcified,
intensely enhancing lesion with a broad dural base in bilateral frontal regions with
marked mass effect suggestive of meningioma. Bilateral frontal craniotomy with gross
tumor excision was performed. Histopathology revealed mesenchymal chondrosarcoma.
Adjuvant radiotherapy was delivered and patient is currently on follow-up. We emphasize
that intracranial mesenchymal chondrosarcoma is a rare neoplasm and should be considered
in the differential diagnoses of intracranial mass along with meningioma. Treatment
of choice is surgery followed by adjuvant radiotherapy. We review the relevant literature
and discuss the characteristics of this rare tumor.
Keywords
mesenchymal chondrosarcoma - intracranial - surgery - radiotherapy