Abstract
In the past 2 decades, molecular hydrogen emerged as a novel therapeutic agent, with
antioxidant, anti-inflammatory and anti-apoptotic effects demonstrated in plethora
of animal disease models and human studies. Beneficial effects of molecular hydrogen
in clinical environment are observed especially in oxidative stress-mediated diseases,
such as diabetes mellitus, brain stem infarction, rheumatoid arthritis, or neurodegenerative
diseases. A number of more recent studies have reported that molecular hydrogen affects
cell signal transduction and acts as an alkalizing agent, with these newly identified
mechanisms of action having the potential to widen its application in clinical medicine
even further. In particular, hydrogen therapy may be an effective and specific innovative
treatment for exercise-induced oxidative stress and sports injury, with potential
for the improvement of exercise performance. This review will summarize recent research
findings regarding the clinical aspects of molecular hydrogen use, emphasizing its
application in the field of sports medicine.
Key words
molecular hydrogen - sports medicine - antioxidant - alkalizing - ergogenic