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Antibacterial and antifungal activity of essential oil of flowers of Lantana camara in Roraima, Brazil
The objective of this study was to determine the chemical composition of the essential oil of flowers of the species Lantana camara collected in Boa Vista city, Roraima, Brazil, and its action against fungi and bacteria. The flowers were collected on Cauamé campus, the essential oil was extracted by hydrodistillation and analyzed by GC-MS. The essential oil yield was 0.31% and the result of chromatographic analysis was 20 chemical constituents, the major components consisting of Germacrene-D (23.7%), Germacrene-B (13.2%), β-Caryophyllene (9.5%), Longicyclene (8.4%) . The yield of the essential oil of flowers of L. camara from Boa Vista, Roraima, Brazil, was consistent with values reported for the oil collected in Southeastern Brazil, 0.33% , but yields reported for oils obtained in Nigeria and Iran were significantly higher, 0.44% and 0.63%, respectively. Differences were also found in the concentration of the chemical components of the essential oil of L. camara flowers. In India , for example, concentrations of germacrene-D Germacrene-B and β-Caryophyllene were lower (10.6, 0.4 and 7.0% respectively) and Longicyclene was not detected. The factors influencing on the yield and composition of essential oils can be climatic, circadian cycle, storage, geographic, among many other . The minimum inhibitory concentration (MIC) of the oil was determined observed against bacteria (Staphylococcus aureus, Streptococcus sanguinis, Escherichia coli, Salmonella typhimurium) and fungi (Candida albicans and C. glabarata). The MIC for the essential oil against pathogenic bacteria tested was 500 µg/mL. Antifungal activities were observed for all concentrations . There is incipient information on antimicrobial activity of essential oil from flowers of L. camara, there are only results for the extracts of flowers , but these preliminary results encourages further investigation.
Keywords: Antimicrobial, volatile oil, germacrene-B, germacrene-D
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