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Endosc Int Open 2015; 03(06): E662-E664
DOI: 10.1055/s-0034-1393076
Original article
© Georg Thieme Verlag KG Stuttgart · New York

Development of a device for detecting target specimens from EUS-guided FNA samples

Kazuya Matsumoto
1   Department of Gastroenterology, Tottori University Hospital, Yonago, Japan
,
Masaru Ueki
2   Center for Promoting Next-Generation Highly Advanced Medicine, Tottori University Hospital, Yonago, Japan
,
Yohei Takeda
1   Department of Gastroenterology, Tottori University Hospital, Yonago, Japan
,
Kenichi Harada
1   Department of Gastroenterology, Tottori University Hospital, Yonago, Japan
,
Takumi Onoyama
1   Department of Gastroenterology, Tottori University Hospital, Yonago, Japan
,
Soichiro Kawata
1   Department of Gastroenterology, Tottori University Hospital, Yonago, Japan
,
Yuichiro Ikebuchi
1   Department of Gastroenterology, Tottori University Hospital, Yonago, Japan
,
Ryu Imamoto
1   Department of Gastroenterology, Tottori University Hospital, Yonago, Japan
,
Yasushi Horie
3   Department of Pathology, Tottori University Hospital, Yonago, Japan
,
Yoshikazu Murawaki
1   Department of Gastroenterology, Tottori University Hospital, Yonago, Japan
› Author Affiliations
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Publication History

Publication Date:
23 September 2015 (online)

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Endoscopy International Open – recently publishedEndoscopy 2015; 47(11): 1061-1061
DOI: 10.1055/s-0034-1393329

Background and study aims: Specimens collected by fine needle are microscopic and contain blood; therefore, the presence of a target specimen within a sample is often difficult to confirm. Although rapid on-site evaluation (ROSE) during endoscopic ultrasound-guided fine needle aspiration biopsy (EUS-FNA) is beneficial, many health care facilities are unable to apply this technique due to a lack of cytopathologists.

The aim of this study was to develop and validate a device that detects the target specimen within pancreatic tumor EUS-FNA samples.

Patients and methods: Fifty-eight consecutive patients with solid pancreatic masses were studied for a preliminary case series at a tertiary-care university hospital (Tottori University Hospital, Yonago, Japan). The material collected was checked with a target sample check illuminator (TSCI) and was evaluated by one cytopathologist.

Results: The agreement rate between the TSCI and histopathology was 93.7 %. Further testing procedures were not needed in 91.4 % of patients, and the mean number of needle punctures was 1.2 after a single pass using TSCI. No adverse events were encountered with the procedure.

Conclusions: With the introduction of the TSCI in EUS-FNA, it became possible to both collect the minimum necessary target samples by EUS-FNA and to end further procedures, even without performing ROSE.

 

  • References

  • 1 Hewitt MJ, McPhail MW, Possamai L et al. EUS-guided FNA for diagnosis of solid pancreatic neoplasm: a meta-analysis. Gastrointest Endosc 2012; 75: 319-331
    CrossrefPubMedGoogle Scholar
  • 2 Madhoun MF, Wani SB, Rastogi A et al. The diagnostic accuracy of 22-gauge and 25-gauge needles in endoscopic ultrasound-guided fine needle aspiration of solid pancreatic lesions: a meta-analysis. Endoscopy 2013; 45: 86-92
    Article in Thieme ConnectPubMedGoogle Scholar
  • 3 Zijlstra WG, Buursma A, Meeuwsen-van der Roest WP. Absorption spectra of human fetal and adult oxyhemoglobin, de-oxyhemoglobin, carboxyhemoglobin, and methemoglobin. Clin Chem 1991; 37: 1633-1638
    CrossrefPubMedGoogle Scholar
  • 4 Matsumoto K, Takeda Y, Harada K et al. The effect of pancreatic juice cytology and/or endoscopic ultrasound-guided fine-needle aspiration biopsy for pancreatic tumor. J Gastroenterol Hepatol 2014; 29: 223-227
    CrossrefPubMedGoogle Scholar