Int Arch Otorhinolaryngol 2015; 19(02): 176-179
DOI: 10.1055/s-0034-1390136
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Thieme Publicações Ltda Rio de Janeiro, Brazil

Olfaction in Neurologic and Neurodegenerative Diseases: A Literature Review

Maria Dantas Costa Lima Godoy
1  Department of Otorhinolaryngology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, São Paulo, Brazil
,
Richard Louis Voegels
1  Department of Otorhinolaryngology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, São Paulo, Brazil
,
Fábio de Rezende Pinna
1  Department of Otorhinolaryngology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, São Paulo, Brazil
,
Rui Imamura
1  Department of Otorhinolaryngology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, São Paulo, Brazil
,
José Marcelo Farfel
2  Department of Geriatrics, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
› Author Affiliations
Further Information

Publication History

16 October 2013

27 July 2014

Publication Date:
14 November 2014 (online)

Abstract

Introduction Loss of smell is involved in various neurologic and neurodegenerative diseases, such as Parkinson disease and Alzheimer disease. However, the olfactory test is usually neglected by physicians at large.

Objective The aim of this study was to review the current literature about the relationship between olfactory dysfunction and neurologic and neurodegenerative diseases.

Data Synthesis Twenty-seven studies were selected for analysis, and the olfactory system, olfaction, and the association between the olfactory dysfunction and dementias were reviewed. Furthermore, is described an up to date in olfaction.

Conclusion Otolaryngologist should remember the importance of olfaction evaluation in daily practice. Furthermore, neurologists and physicians in general should include olfactory tests in the screening of those at higher risk of dementia.