Int Arch Otorhinolaryngol 2014; 18 - a2289
DOI: 10.1055/s-0034-1388923

Clivus Lymphoma

Mila Macedo Almeida 1, Priscila Fontinele Muniz 1, Diego Lima 1, Fabio Pinna 1, Richard Voegels 1, Gilberto Ochman 1
  • 1Hospital das Clínicas da Faculdade de Medicina, Universidade de São Paulo (HC-FM-USP)

Introduction: Burkitt lymphoma (BL) is estimated to correspond only for 1 to 5% of all nonHodgkin lymphomas in adults. Most BL usually involves the jaw, while the majority of sporadic type often presents in the abdomen. Involvement of Central Nervous System (CNS) diagnosis is reported from 4 to 27% of patients.

Aim: This study aims to report a BL case in clivus.

Report: A 38-year-old female patient (R. F. S.), HIV positive, complains from frontal and retroorbitaria headache, pulsatile on insidious beginning, progressive, for 3 months. At physical examination, commitment of cranial nerve (CN) XII on the right was observed. About the 7th day of hospitalization, she developed sudden diplopia associated with psychomotor slowing, bilateral papiledema, involvement of II cranial pair bilaterally, III on the left and V, IX, X, and XII on the right. CT image present soft-tissue density occupying sphenoid sinus with invasion of turcica sella and clivus. RNM: expansive lesion in esfenoide and clivus topography, with extension to rinofaringe, turcica sela and cavernous sinus. The patient was submitted to an esfenoidotomy and fragments of the tumor were sent to histopathology. The patient was diagnosed with BL of clivus. After a diagnosis conclusion, the patient was submitted to a chemotherapy which protocol was determined by oncology team.

Conclusion: Despite a rare condition, it is important to include lymphoma as a differential diagnosis for lesions on clivus.