J Neurol Surg B Skull Base 2014; 75 - a052
DOI: 10.1055/s-0034-1383958

Outcomes and Prognostic Analysis of Petroclival Meningiomas in Chinese Patients: A Single-Center Case Series of 259 Surgically Treated Patients

J. T. Zhang 1
  • 1Beijing Tiantan Hospital, Capital Medical University, Beijing, Peoples Republic of China

Objective: To evaluate the clinical outcome and prognostic factors of petroclival meningiomas during a long-term follow-up period after microsurgical resection. Methods: A series of 259 patients with petroclival meningiomas (70 males and 189 females) were surgically treated. Clinical charts and radiographs were reviewed, and follow-up results were evaluated. Results: The preoperative Karnofsky performance scale (KPS) score was 74.2¡À10.5. The gross-total resection (GTR) rate was 52.5%. The postoperative KPS at discharge was 66.4¡À11.9. The recent KPS score was 78.4¡À22.7, and it improved in 139 (57.2%) patients, stabilized in 53 (21.8%) patients, and 201 (82.7%) patients lived independently. After R/P, the survival significantly differed between patients with or without treatment (p = 0.006). The risk factors affecting the KPS score included (but were not limited to) age¡Ý60, preoperative KPS¡Ü60, nontotal resection, and brainstem edema. The factors contributing to R/P-free survival included (but were not limited to) nontotal resection, the absence of the subarachnoid space, and WHO grade II tumors. Conclusion: Favorable outcomes from petroclival meningiomas could be achieved by microsurgery. Neurological function and quality of life were prioritized, and GTR was attempted. Risk factors should be considered in surgical schemes, and tumor recurrence should be aggressively monitored and treated.