DART-MS analysis of Glycyrrhiza species

J Henkin; B Wright; A Newsome; RB van Breemen

doi:10.1055/s-0034-1382670

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Planta Med 2014; 80 - PPL34
DOI: 10.1055/s-0034-1382670

DART-MS analysis of Glycyrrhiza species

J Henkin ¹, B Wright ¹, A Newsome ¹, RB van Breemen ¹

¹Department of Medicinal Chemistry and Pharmacognosy, 833 S. Wood Street Chicago, IL 60612

Congress Abstract

Requiring no chromatography, Direct Analysis in Real Time (DART)-mass spectrometric analysis was performed on ethanolic extracts of Glycyrrhiza spp. Characteristic mass spectra of G. uralensis, G. inflata, and G. glabra were obtained and compared. Positive ion DART-MS analysis of G. uralensis showed characteristic ions including m/z 313, 339 and 479, while analysis of G. inflata and G. glabra yielded distinctly different yet characteristic mass spectra. This work demonstrates an extremely beneficial application of DART-MS as a rapid technique to aid in the identification and distinction of plant species. Supported by grant P50 AT000155 from the NIH/ODS and NIH/NCCAM.