Planta Med 2014; 80 - PD102
DOI: 10.1055/s-0034-1382523

Seven C19-norditerpenoid alkaloids from Delphinium elatum

R Chiba 1, R Kanazawa 1, K Matsuoka 1, A Nakata 1, Y Tosho 1, E Asakawa 1, M Suzuki 1, M Ikuta 1, H Yamashita 1, K Wada 1
  • 1Medicinal Chemistry, School of Pharmacy, Hokkaido Pharmaceutical University, 7 – 1, Katsuraoka-cho, Otaru 047 – 0264, Japan

Seven new C19-norditerpenoid alkaloids, N-formyl-4,19-secopacinine (1), iminoisodelpheline (2), iminodelpheline (3), iminopaciline (4), 6-dehydroeladine (5), elpacidine (6), and melpheline (7), have been isolated from Delphinium elatum cv. Pacific Giant together with six known C19-norditerpenoid alkaloids, delpheline, pacinine, isodelpheline, yunnadelphinine, delcorine, and 6-dehydrodelcorine. The structures of these alkaloids were determined by their ms, 1D and 2D-nmr data. 6-Dehydrodelcorine were isolated which have not previously been found in this plant.

Fig. 1