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Synlett 2015; 26(15): 2185-2186
DOI: 10.1055/s-0034-1381164
DOI: 10.1055/s-0034-1381164
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Bromoacetaldehyde Diethyl Acetal
Further Information
Publication History
Publication Date:
12 August 2015 (online)
Introduction
Bromoacetaldehyde diethyl acetal (1) is widely used in chemistry for the synthesis of a variety of antibiotics (including erythromycin and cephalosporins) and other drugs. It is an important and highly reactive bifunctional compound with a good leaving group and a masked aldehyde function. It can be used as a starting material in a variety of reactions to provide N-alkylated compounds,[1] lactams,[2] aldehydes,[3] oximes,[4] azides,[5] and acyclic di-/polyselenides.[3]
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References
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