Synlett 2015; 26(06): 839-845
DOI: 10.1055/s-0034-1380124
letter
© Georg Thieme Verlag Stuttgart · New York

Synthesis and Selenation of Tandem Multicomponent Condensation Adducts

Guoxiong Hua
EaStCHEM School of Chemistry, University of St Andrews, Fife, KY16 9ST, UK   Email: [email protected]
,
Junyi Du
EaStCHEM School of Chemistry, University of St Andrews, Fife, KY16 9ST, UK   Email: [email protected]
,
Amy L. Fuller
EaStCHEM School of Chemistry, University of St Andrews, Fife, KY16 9ST, UK   Email: [email protected]
,
Kasun S. A. Arachchige
EaStCHEM School of Chemistry, University of St Andrews, Fife, KY16 9ST, UK   Email: [email protected]
,
David B. Cordes
EaStCHEM School of Chemistry, University of St Andrews, Fife, KY16 9ST, UK   Email: [email protected]
,
Alexandra M. Z. Slawin
EaStCHEM School of Chemistry, University of St Andrews, Fife, KY16 9ST, UK   Email: [email protected]
,
J. Derek Woollins*
EaStCHEM School of Chemistry, University of St Andrews, Fife, KY16 9ST, UK   Email: [email protected]
› Author Affiliations
Further Information

Publication History

Received: 10 November 2014

Accepted after revision: 23 December 2014

Publication Date:
03 February 2015 (online)


Abstract

A number of four-component condensation adducts, which were readily obtained from one-pot reaction of aryl carboxylic acids, arylaldehydes, arylamines, and c-hexylisocyanide, were treated with two equivalents of Woollins’ reagent leading to the formation of a series of novel selenoamides with one or two C=Se groups or heterocyclic compounds such as 1,3-selenazole and 1,3-selenazolidin-5-one.

Supporting Information

 
  • References and Notes

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  • 51 X-ray data for compounds 1, 2, 4, 6, 11, and 13 (CCDC 1017055 through 1017060) can be obtained free of charge via www.ccdc.cam.ac.uk/conts/retrieving.html or from the Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge CB2 1EZ, UK; fax +44(1223)336033; e-mail: [email protected]