J Neurol Surg Rep 2014; 75(01): e122-e128
DOI: 10.1055/s-0034-1376425
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Cavernous Sinus Angioleiomyoma: Case Report and Review of the Literature

Yu Teranishi
1   Department of Neurosurgery and Stroke Center, Tokyo Metropolitan Police Hospital, Tokyo, Japan
,
Michihiro Kohno
1   Department of Neurosurgery and Stroke Center, Tokyo Metropolitan Police Hospital, Tokyo, Japan
,
Shigeo Sora
1   Department of Neurosurgery and Stroke Center, Tokyo Metropolitan Police Hospital, Tokyo, Japan
,
Hiroaki Sato
1   Department of Neurosurgery and Stroke Center, Tokyo Metropolitan Police Hospital, Tokyo, Japan
,
Munehiro Yokoyama
2   Department of Pathology, Tokyo Metropolitan Police Hospital, Tokyo, Japan
› Author Affiliations
Further Information

Publication History

05 October 2013

15 March 2014

Publication Date:
04 June 2014 (online)

Abstract

Cavernous sinus angioleiomyoma (ALM) is extremely rare. Only three cases have been reported to be cavernous sinus ALM, and very few reports described characteristic findings for intracranial ALMs in detail. We report a new case of cavernous sinus ALM, with detailed information on the clinical presentation, radiology, pathology, and surgical approach. A 52-year-old woman had a 6-month history of right eye discomfort. Magnetic resonance imaging showed a right cavernous sinus tumor with heterogenous blush enhancement. Enhanced computed tomography scans and angiography showed small nodular enhancement in the tumor. Complete tumor resection was achieved via an extradural temporopolar approach. ALM was identified based on histologic examination. Intracranial ALMs are different from the ALMs that occur in the extremities based on our review of the literature. Intracranial ALMs appear more frequently in men than women. The cavernous type was the most common pathologically, and they occur often in the epiperidural location. Because cavernous sinus ALM occurs in the interdural space, an epidural approach should be selected. Therefore, it is important to include cavernous sinus ALM into a differential diagnosis of a cavernous sinus tumor. The blush enhancement and nodular enhancement within this lesion may be useful to distinguish cavernous sinus ALM from other differential diagnoses.

 
  • References

  • 1 Colnat-Coulbois S, Schmitt E, Klein O, Weinbreck N, Auque J, Civit T. Angioleiomyoma of the cavernous sinus: case report. Neurosurgery 2008; 62 (1) E257 –E258; discussion E258
  • 2 Figueiredo EG, Gomes M, Vellutini E, Rosemberg S, Marino Jr R. Angioleiomyoma of the cavernous sinus: case report. Neurosurgery 2005; 56 (2) E411 ; discussion E411
  • 3 Zhou Z, Yu M, Yang S, Zhou J, Sun R, Yang G. Dural angioleiomyoma of the middle cranial fossa: a case report and review of the literature. Brain Tumor Pathol 2013; 30 (2) 117-121
  • 4 Hachisuga T, Hashimoto H, Enjoji M. Angioleiomyoma. A clinicopathologic reappraisal of 562 cases. Cancer 1984; 54 (1) 126-130
  • 5 Gasco J, Franklin B, Rangel-Castilla L, Campbell GA, Eltorky M, Salinas P. Infratentorial angioleiomyoma: a new location for a rare neoplastic entity. J Neurosurg 2009; 110 (4) 670-674
  • 6 Karagama YG, Bridges LR, van Hille PT. Angioleiomyoma of the internal auditory meatus: a rare occurrence in the internal auditory canal. Ear Nose Throat J 2005; 84 (4) 216-218
  • 7 Kohan D, Downey LL, Lim J, Cohen NL, Elowitz E. Uncommon lesions presenting as tumors of the internal auditory canal and cerebellopontine angle. Am J Otol 1997; 18 (3) 386-392
  • 8 Lach B, Duncan E, Rippstein P, Benoit BG. Primary intracranial pleomorphic angioleiomyoma—a new morphologic variant. An immunohistochemical and electron microscopic study. Cancer 1994; 74 (7) 1915-1920
  • 9 Ravikumar C, Veerendrakumar M, Hegde T, Nagaraja D, Jayakumar PN, Shankar SK. Basal ganglionic angioleiomyoma. Clin Neurol Neurosurg 1996; 98 (3) 253-257
  • 10 Shinde SV, Shah AB, Baviskar RB, Deshpande JR. Primary intracranial multicentric angioleiomyomas. Neurol India 2012; 60 (1) 115-117
  • 11 Conner TM, Waziri A, Kleinschmidt-Demasters BK. Angioleiomyomas of the dura: rare entities that lack KRIT1 mutations. Am J Surg Pathol 2012; 36 (4) 526-533
  • 12 Vijayasaradhi M, Uppin SG, Sreedhar V, Sundaram C, Panigrahi MK. Frontal intradiploic angioleiomyoma. J Neurosurg Pediatr 2008; 2 (4) 266-268
  • 13 Xu Y, Jing Y, Ma S , et al. Primary angioleiomyoma in the sellar region: a case report and literature review. Clin Neuropathol 2010; 29 (1) 21-25
  • 14 Ramesh P, Annapureddy SR, Khan F, Sutaria PD. Angioleiomyoma: a clinical, pathological and radiological review. Int J Clin Pract 2004; 58 (6) 587-591
  • 15 Huang MC, van Loveren H . Anatomy and biology of the leptomeninges. In: Al-Mefty O, ed. Meningiomas. New York, NY: Raven Press; 1991. :Chapter 3