Semin intervent Radiol 2014; 31(02): 149-156
DOI: 10.1055/s-0034-1373797
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Image-Guided Ablation of Adrenal Lesions

Koichiro Yamakado
1   Department of Interventional Radiology, Mie University School of Medicine, Mie, Japan
› Author Affiliations
Further Information

Publication History

Publication Date:
21 May 2014 (online)

Abstract

Although laparoscopic adrenalectomy has remained the standard of care for the treatment for adrenal tumors, percutaneous image-guided ablation therapy, such as chemical ablation, radiofrequency ablation, cryoablation, and microwave ablation, has been shown to be clinically useful in many nonsurgical candidates. Ablation therapy has been used to treat both functioning adenomas and malignant tumors, including primary adrenal carcinoma and metastasis. For patients with functioning adenomas, biochemical and symptomatic improvement is achieved in 96 to 100% after ablation; for patients with malignant adrenal neoplasms, however, the survival benefit from ablation therapy remains unclear, though good initial results have been reported. This article outlines the current role of ablation therapy for adrenal lesions, as well as identifying some of the technical considerations for this procedure.

 
  • References

  • 1 Ethier MD, Beland MD, Mayo-Smith W. Image-guided ablation of adrenal tumors. Tech Vasc Interv Radiol 2013; 16 (4) 262-268
  • 2 Uppot RN, Gervais DA. Imaging-guided adrenal tumor ablation. AJR Am J Roentgenol 2013; 200 (6) 1226-1233
  • 3 Liang HL, Pan HB, Lee YH , et al. Small functional adrenal cortical adenoma: treatment with CT-guided percutaneous acetic acid injection—report of three cases. Radiology 1999; 213 (2) 612-615
  • 4 Al-Shaikh AA, Al-Rawas MM, Al-Asnag MA. Primary hyperaldosteronism treated by radiofrequency ablation. Saudi Med J 2004; 25 (11) 1711-1714
  • 5 Mendiratta-Lala M, Brennan DD, Brook OR , et al. Efficacy of radiofrequency ablation in the treatment of small functional adrenal neoplasms. Radiology 2011; 258 (1) 308-316
  • 6 Liu SY, Ng EK, Lee PS , et al. Radiofrequency ablation for benign aldosterone-producing adenoma: a scarless technique to an old disease. Ann Surg 2010; 252 (6) 1058-1064
  • 7 Arima K, Yamakado K, Suzuki R , et al. Image-guided radiofrequency ablation for adrenocortical adenoma with Cushing syndrome: outcomes after mean follow-up of 33 months. Urology 2007; 70 (3) 407-411
  • 8 Mayo-Smith WW, Dupuy DE. Adrenal neoplasms: CT-guided radiofrequency ablation—preliminary results. Radiology 2004; 231 (1) 225-230
  • 9 Xiao YY, Tian JL, Li JK, Yang L, Zhang JS. CT-guided percutaneous chemical ablation of adrenal neoplasms. AJR Am J Roentgenol 2008; 190 (1) 105-110
  • 10 Wolf FJ, Dupuy DE, Machan JT, Mayo-Smith WW. Adrenal neoplasms: effectiveness and safety of CT-guided ablation of 23 tumors in 22 patients. Eur J Radiol 2012; 81 (8) 1717-1723
  • 11 Yamakado K, Takaki H, Yamada T , et al. Incidence and cause of hypertension during adrenal radiofrequency ablation. Cardiovasc Intervent Radiol 2012; 35 (6) 1422-1427
  • 12 Wood BJ, Abraham J, Hvizda JL, Alexander HR, Fojo T. Radiofrequency ablation of adrenal tumors and adrenocortical carcinoma metastases. Cancer 2003; 97 (3) 554-560
  • 13 Atwell TD, Wass CT, Charboneau JW, Callstrom MR, Farrell MA, Sengupta S. Malignant hypertension during cryoablation of an adrenal gland tumor. J Vasc Interv Radiol 2006; 17 (3) 573-575
  • 14 Yamakado K, Anai H, Takaki H , et al. Adrenal metastasis from hepatocellular carcinoma: radiofrequency ablation combined with adrenal arterial chemoembolization in six patients. AJR Am J Roentgenol 2009; 192 (6) W300-W305
  • 15 Carrafiello G, Laganà D, Recaldini C , et al. Imaging-guided percutaneous radiofrequency ablation of adrenal metastases: preliminary results at a single institution with a single device. Cardiovasc Intervent Radiol 2008; 31 (4) 762-767
  • 16 Wang Y, Liang P, Yu X, Cheng Z, Yu J, Dong J. Ultrasound-guided percutaneous microwave ablation of adrenal metastasis: preliminary results. Int J Hyperthermia 2009; 25 (6) 455-461
  • 17 Shibata T, Maetani Y, Ametani F, Itoh K, Konishi J. Percutaneous ethanol injection for treatment of adrenal metastasis from hepatocellular carcinoma. AJR Am J Roentgenol 2000; 174 (2) 333-335
  • 18 Li X, Fan W, Zhang L , et al. CT-guided percutaneous microwave ablation of adrenal malignant carcinoma: preliminary results. Cancer 2011; 117 (22) 5182-5188
  • 19 Welch BT, Atwell TD, Nichols DA , et al. Percutaneous image-guided adrenal cryoablation: procedural considerations and technical success. Radiology 2011; 258 (1) 301-307
  • 20 Venkatesan AM, Locklin J, Lai EW , et al. Radiofrequency ablation of metastatic pheochromocytoma. J Vasc Interv Radiol 2009; 20 (11) 1483-1490
  • 21 Tsoumakidou G, Buy X, Zickler P, Zupan M, Douchet MP, Gangi A. Life-threatening complication during percutaneous ablation of adrenal gland metastasis: Takotsubo syndrome. Cardiovasc Intervent Radiol 2010; 33 (3) 646-649
  • 22 Chini EN, Brown MJ, Farrell MA, Charboneau JW. Hypertensive crisis in a patient undergoing percutaneous radiofrequency ablation of an adrenal mass under general anesthesia. Anesth Analg 2004; 99 (6) 1867-1869
  • 23 Lo WK, vansonnenberg E, Shankar S , et al. Percutaneous CT-guided radiofrequency ablation of symptomatic bilateral adrenal metastases in a single session. J Vasc Interv Radiol 2006; 17 (1) 175-179
  • 24 Onik G, Onik C, Medary I , et al. Life-threatening hypertensive crises in two patients undergoing hepatic radiofrequency ablation. AJR Am J Roentgenol 2003; 181 (2) 495-497
  • 25 Demeure MJ, Somberg LB. Functioning and nonfunctioning adrenocortical carcinoma: clinical presentation and therapeutic strategies. Surg Oncol Clin N Am 1998; 7 (4) 791-805
  • 26 Pommier RF, Brennan MF. An eleven-year experience with adrenocortical carcinoma. Surgery 1992; 112 (6) 963-970 , discussion 970–971
  • 27 Sung GT, Gill IS. Laparoscopic adrenalectomy. Semin Laparosc Surg 2000; 7 (3) 211-222
  • 28 Paul CA, Virgo KS, Wade TP, Audisio RA, Johnson FE. Adrenalectomy for isolated adrenal metastases from non-adrenal cancer. Int J Oncol 2000; 17 (1) 181-187
  • 29 Lo CY, van Heerden JA, Soreide JA , et al. Adrenalectomy for metastatic disease to the adrenal glands. Br J Surg 1996; 83 (4) 528-531
  • 30 Kim SH, Brennan MF, Russo P, Burt ME, Coit DG. The role of surgery in the treatment of clinically isolated adrenal metastasis. Cancer 1998; 82 (2) 389-394
  • 31 Yamakado K, Nakatsuka A, Takaki H , et al. Early-stage hepatocellular carcinoma: radiofrequency ablation combined with chemoembolization versus hepatectomy. Radiology 2008; 247 (1) 260-266
  • 32 Yamakado K, Takaki H, Uchida K, Nakatsuka A, Shiraishi T, Takeda K. Adrenal radiofrequency ablation in swine: change in blood pressure and histopathologic analysis. Cardiovasc Intervent Radiol 2011; 34 (4) 839-844
  • 33 Tatli S, Morrison PR, Tuncali K, Silverman SG. Interventional MRI for oncologic applications. Tech Vasc Interv Radiol 2007; 10 (2) 159-170
  • 34 Goldberg SN, Grassi CJ, Cardella JF , et al; Society of Interventional Radiology Technology Assessment Committee and the International Working Group on Image-guided Tumor Ablation. Image-guided tumor ablation: standardization of terminology and reporting criteria. J Vasc Interv Radiol 2009; 20 (7, Suppl): S377-S390
  • 35 Livraghi T, Goldberg SN, Lazzaroni S, Meloni F, Solbiati L, Gazelle GS. Small hepatocellular carcinoma: treatment with radio-frequency ablation versus ethanol injection. Radiology 1999; 210 (3) 655-661
  • 36 Farrell MA, Charboneau JW, Callstrom MR, Reading CC, Engen DE, Blute ML. Paranephric water instillation: a technique to prevent bowel injury during percutaneous renal radiofrequency ablation. AJR Am J Roentgenol 2003; 181 (5) 1315-1317
  • 37 Takaki H, Nakatsuka A, Uraki J , et al. Renal cell carcinoma: radiofrequency ablation with a multiple-electrode switching system—a phase II clinical study. Radiology 2013; 267 (1) 285-292