Intraoperative Neural Response Telemetry and Neural Recovery Function: a Comparative Study between Adults and Children
10 December 2013
11 February 2014
02 April 2014 (eFirst)
Introduction Neural response telemetry (NRT) is a method of capturing the action potential of the distal portion of the auditory nerve in cochlear implant (CI) users, using the CI itself to elicit and record the answers. In addition, it can also measure the recovery function of the auditory nerve (REC), that is, the refractory properties of the nerve. It is not clear in the literature whether the responses from adults are the same as those from children.
Objective To compare the results of NRT and REC between adults and children undergoing CI surgery.
Methods Cross-sectional, descriptive, and retrospective study of the results of NRT and REC for patients undergoing IC at our service. The NRT is assessed by the level of amplitude (microvolts) and REC as a function of three parameters: A (saturation level, in microvolts), t0 (absolute refractory period, in seconds), and tau (curve of the model function), measured in three electrodes (apical, medial, and basal).
Results Fifty-two patients were evaluated with intraoperative NRT (26 adults and 26 children), and 24 with REC (12 adults and 12 children). No statistically significant difference was found between intraoperative responses of adults and children for NRT or for REC's three parameters, except for parameter A of the basal electrode.
Conclusion The results of intraoperative NRT and REC were not different between adults and children, except for parameter A of the basal electrode.
- 1 Guedes MC, Brito Neto RV, Gomez MV , et al. Neural response telemetry measures in patients implanted with Nucleus 24. Braz J Otorhinolaryngol 2005; 71 (5) 660-667
- 2 Ferrari DV, Sameshima K, Costa Filho OA, Bevilacqua MC. Neural response telemetry on the nucleus 24 multichannel cochlear implant system: literature review. Rev Bras Otorrinolaringol 2004; 70 (1) 112-118
- 3 Tanamati LF, Bevilacqua MC, Costa OA. Longitudinal study of the ecap measured in children with cochlear implants. Braz J Otorhinolaryngol 2009; 75 (1) 90-96
- 4 Kutscher K, Goffi-Gomez MV, Befi-Lopes DM, Tsuji RK, Bento RF. Cochlear implant: correlation of nerve function recovery, auditory deprivation and etiology. Pro Fono 2010; 22 (4) 473-478
- 5 Botros A, Psarros C. Neural response telemetry reconsidered: II. The influence of neural population on the ECAP recovery function and refractoriness. Ear Hear 2010; 31 (3) 380-391
- 6 Botros A, Psarros C. Neural response telemetry reconsidered: I. The relevance of ECAP threshold profiles and scaled profiles to cochlear implant fitting. Ear Hear 2010; 31 (3) 367-379
- 7 Gantz BJ, Brown CJ, Abbas PJ. Intraoperative measures of electrically evoked auditory nerve compound action potential. Am J Otol 1994; 15 (2) 137-144
- 8 Gordon KA, Papsin BC, Harrison RV. An evoked potential study of the developmental time course of the auditory nerve and brainstem in children using cochlear implants. Audiol Neurootol 2006; 11 (1) 7-23
- 9 Lai W. An NRT Cookbook: Guidelines for Making NRT Measurements. 1st ed. Zürich, Switzerland: Cochlear AG; 1999
- 10 Bento RF, Brito Neto R, Castilho AM, Gomez VG, Giorgi SB, Guedes MC. Auditory results with multicanal cochlear implant in patients submitted to cochlear implant surgery at University of São Paulo Medical School–Hospital das Clínicas. Rev Bras Otorrinolaringol 2004; 70 (5) 632-637
- 11 Miller CA, Brown CJ, Abbas PJ, Chi SL. The clinical application of potentials evoked from the peripheral auditory system. Hear Res 2008; 242 (1–2) 184-197
- 12 Gordon KA, Ebinger KA, Gilden JE, Shapiro WH. Neural response telemetry in 12- to 24-month-old children. Ann Otol Rhinol Laryngol Suppl 2002; 189: 42-48