Abstract
Current research states that AIDS pathogenesis has its roots in a chronic activation
of immune system secondary to human immunodeficiency virus (HIV)–induced proliferation
of T cells, B cells, NK cells, and macrophages. Immune activation due to acute HIV
infection can be highly detrimental to allograft survival in a renal transplant recipient.
In this report, we describe a 32-year-old African-American male patient who underwent
a second live donor renal transplant, following which he developed acute allograft
rejection coincident with newly acquired HIV seropositivity.
Keywords
allograft - HIV - immunosuppression - AIDS - renal transplant
