Third Ventricular Glioblastoma Multiforme: Case Report and Literature Review
Glioblastoma multiforme (GBM) typically presents in the cerebrum, localized to the frontal, temporal, or parietal lobes as a ring-enhanced lesion, with areas of necrosis on Magnetic Resonance Imaging (MRI). We present a case of a sixty-two year old female with headaches, increasing somnolence and cognitive decline for several weeks. MRI imaging showed mild hydrocephalus with well marginated, homogenous, and non-hemorrhagic lesion of posterior third ventricle extending between the leafs of the septum pellucidum, and the body of the fornix without evidence of either necrosis or ring enhancement on post-contrast T1-weighted MRI. Final pathology reports confirmed the diagnosis of GBM. This case report describes a very unusual location for the most common primary brain neoplasm. Moreover, this case identifies the origin of a GBM related to the paracentral ventricular structures interpositioning itself between the body of the fornix and leafs of the septum pellucidum. Interestingly, the radiographic findings did not present any evidence or typical characteristic of a GBM in this patient. To our knowledge this is the first reported case of a GBM found in this anatomical location, with such atypical radiographic presentation.