Übersicht – Möglichkeiten der molekularen Diagnostik von Nierenzelltumoren

Nierenzellkarzinome (NZK) haben einen Anteil von 3% an allen malignen Erkrankungen im Erwachsenenalter. Es ist heute klar belegt, dass die primär histologisch definierten Subtypen (klarzellig, papillär, chromophob, Onkozytom) aufgrund ihrer spezifischen differenten molekularen Veränderungen sowie der unterschiedlichen Prognose als eigenständige Tumorentitäten betrachtet werden müssen.

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