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Int Arch Otorhinolaryngol 2014; 18(03): 255-259
DOI: 10.1055/s-0034-1366976
Original Research
Thieme Publicações Ltda Rio de Janeiro, Brazil

Language in Children with Neonatal Hypoxic-Ischemic Encephalopathy

Chenia Martinez
1   Departamento de Fonoaudiologia, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brazil
,
Luciana Carneiro
1   Departamento de Fonoaudiologia, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brazil
,
Luíza Vernier
1   Departamento de Fonoaudiologia, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brazil
,
Carla Cesa
2   Faculdade Nossa Senhora de Fátima, Caxias do Sul, RS, Brazil
,
Ana Guardiola
3   Departamento de Neurologia, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brazil
,
Deisi Vidor
4   Departamento da Pró-reitoria de Extensão de Assuntos Comunitários, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brazil
› Author Affiliations
Further Information

Publication History

09 October 2013

08 December 2013

Publication Date:
10 February 2014 (online)

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Abstract

Introduction Neonatal hypoxic-ischemic encephalopathy (NHIE) is a common neurologic injury, and it may compromise the child's language and cognition. Understanding the process of language acquisition becomes possible with concise knowledge about children's global development.

Objective The aim of this study was to observe if language acquisition and development are impaired in children with NHIE.

Methods Seventy children with NHIE from 1 to 24 months old were analyzed in a Pediatric Neurology Service of Hospital of Porto Alegre, South of Brazil using the Brunet-Lezine Scale. Statistical analysis used SPSS 13.0 software.

Results Twenty-four (60%) of the subjects were boys, with mean gestational age of 35.8 weeks (standard deviation of 4.6) and mean Apgar score of 6.0 at 1 minute and 7.1 at 5 minutes. The variables age versus language showed significant inverse correlation (r =  − 0.566; p = 0.028). As the subjects aged, language tasks became more specific and dependent on the subject's direct action, rather than the subjective interpretation of their guardian. This correlation seems to be closely associated with scale configuration and with consequences of neurologic disorder, evincing the delays in language development.

Conclusion This study achieved the goals proposed and highlights the necessity of greater attention by professionals to language skills during the initial period of child development.

Keywords

language development - hypoxia - brain - brain ischemia - neurology - speech - language - and hearing sciences
 

  • References

  • 1 Diament A, Cypel S. Neurologia infantil. 4ª ed. Vol. 2. São Paulo Brazil: Atheneu; 2005
    Google Scholar
  • 2 Wyatt JS, Gluckman PD, Liu PY , et al; CoolCap Study Group. Determinants of outcomes after head cooling for neonatal encephalopathy. Pediatrics 2007; 119 (5) 912-921
    CrossrefPubMedGoogle Scholar
  • 3 Corrêa RRM, Salge AKM, Ribeiro GA. Anatomic and pathological placenta alterations and Apgar score variations. Rev Bras Saude Mater Infant 2006; 6 (2) 239-243
    CrossrefGoogle Scholar
  • 4 Cruz ACS, Ceccon MEJ. Prevalence of asphyxia and perinatal hypoxic-ischemic encephalopathy in term newborns, considering two diagnostic criteria. Rev Bras Crescimento Desenvolv Hum 2010; 20 (2) 302-316
    Google Scholar
  • 5 Volpe JJ. Neurology of the Newborn. 4th ed. Philadelphia PA: W.B. Saunders; 2001: 217-394
    Google Scholar
  • 6 Zorzi JL. A intervenção fonoaudiológica nas alterações da linguagem infantil. 2 ed. Rio de Janeiro Brazil: Revinter; 2002
    Google Scholar
  • 7 Oliveira JP , et al. Communicative profile of children who entered in primary school after the age of five. Rev Bras Promoc Saude (Impr.) 2010; 23 (2) 160-167
    CrossrefGoogle Scholar
  • 8 Amorim R. Avaliação da criança com alteração da linguagem. Nascer e Crescer 2011; 20 (3) 174-176
    Google Scholar
  • 9 Scopel RR, Souza VC, Lemos SMA. A influência do ambiente familiar e escolar na aquisição e no desenvolvimento da linguagem: revisão de literatura. Rev CEFAC. 2012; 14 (4) 732-741 . Available at: http://dx.doi.org/10.1590/S1516-18462011005000139 . Accessed in Sep 18, 2013
    CrossrefGoogle Scholar
  • 10 Zorzi JL. Aspectos básicos para compreensão, diagnóstico e prevenção dos distârbios de linguagem na infância. Rev CEFAC 2000; 2 (1) 11-15
    Google Scholar
  • 11 Dale PS, Patterson JL, Identificação precoce de atrasos de linguagem. In: Tremblay RE, Boivin M, Peters RDV. eds. Enciclopédia sobre o Desenvolvimento da Primeira Infância. Montreal Quebec: Centre of Excellence for Early Childhood Development; 2011: 1-6 . Available at: http://www.enciclopedia-crianca.com/documents/Dale-PattersonPRTxp1-Linguagem.pdf . Accessed in July 8, 2013
    Google Scholar
  • 12 Befi-Lopes DM, Gândara JP, Felisbino FS. Categorização semântica e aquisição lexical: desempenho de crianças com alteração do desenvolvimento da linguagem. Rev CEFAC 2006; 8 (2) 155-161
    Google Scholar
  • 13 Pedroso FS, Rotta NT, Danesi MC, Ávila LN, Sávio CB. Evolução das manifestções pré-linguísticas em crianças normais no primeiro ano de vida. Rev Soc Bras Fonoaudiol. 2009; 14 (1) 22-25
    Google Scholar
  • 14 Lee LL, Harris SR. Psychometric properties and standardization samples of four screening tests for infants and young children: a review. Pediatr Phys Ther 2005; 17 (2) 140-147
    CrossrefGoogle Scholar
  • 15 Santos RS, Araujo APQC, Porto MAS. Diagnóstico precoce de anormalidades no desenvolvimento em prematuros: instrumentos de avaliação. J Pediatr 2008; 84 (4) 289-299
    Google Scholar
  • 16 Kim SW, Han ZA, Jeon HR , et al. Neurodevelopmental disorders of children screened by the infantile health promotion system. Ann Rehabil Med 2011; 35 (6) 867-872
    CrossrefGoogle Scholar
  • 17 Brunet O, Lézine I. Desenvolvimento psicológico da primeira infância. Tradução de Ana Guardiola Brizolara. Porto Alegre, Brazil: Artes Médicas; 1981
    Google Scholar
  • 18 Egewarth C, Pires FDA, Guardiola A. Avaliação da idade gestacional de recém nascidos pré-termo através do exame neurológico e das escalas neonatais e obstétrica. Arq Neuropsiquiatr 2002; 60 (3–B): 755-759
    CrossrefGoogle Scholar
  • 19 Ayache MG, Mariani Neto C. Considerations on the motor development of the premature. Temas Desenvolv 2003; 12 (7) 5-9
    Google Scholar
  • 20 Oliveira LN, Lima MCMP, Gonçalves VMG. Acompanhamento de lactentes com baixo peso ao nascimento: aquisição da linguagem. Arq Neuropsiquiatr 2003; 61 (3B): 802-807
    CrossrefGoogle Scholar
  • 21 Zomignani AP, Zambelli HJL, Antônio MARGM. Cerebral development in preterm newborn infants. Rev Paul Pediatr. 2009; 27 (2) 63-67
    Google Scholar
  • 22 Rocha SR, Dornelas LF, Magalhães LC. Assessment tools utilized for the evaluation of preterm neonates in Brazil: literature review. Cad Ter Ocup UFSCar 2013; 21 (1) 109-117
    Google Scholar
  • 23 Escobar GJ, Mccormick MC, Zupancic JA , et al. Unstudied infants: outcomes of moderately premature infants in the neonatal intensive care unit. Arch Dis Child Fetal Neonatal Ed 2006; 91 (4) F238-244
    CrossrefGoogle Scholar
  • 24 van Noort-van der Spek IL, Franken MC, Weisglas-Kuperus N. Language functions in preterm-born children: a systematic review and meta-analysis. Pediatrics 2012; 129 (4) 745-754
    CrossrefGoogle Scholar
  • 25 American Academy of Pediatrics, Committee on Fetus and Newborn American College of Obstetricians and Gynecologists, Committee on Obstetric Practice. The Apgar score. Pediatrics 2006; 117: 1444-7 . Available at: www.pediatrics.org/cgi/doi/10.1542/peds.2006-0325 . Accessed in Aug 23, 2013
    CrossrefGoogle Scholar
  • 26 American College of Obstetrics and Gynecology, Task Force on Neonatal Encephalopathy and Cerebral Palsy. American Academy of Pediatrics. Neonatal Encephalopathy and Cerebral Palsy: Defining the Pathogenesis and Pathophysiology. Washington, DC: American College of Obstetricians and Gynecologists; 2003
    Google Scholar
  • 27 Salustiano EMA, Campos JA, Ibidi SM, Ruano R, Zugaib M. Low Apgar scores at 5 minutes in a low risk population: maternal and obstetrical factors and postnatal outcome. Rev Assoc Med Bras 2012; 58 (5) 587-593
    CrossrefGoogle Scholar
  • 28 Kandel ER, Schamartz JH, Jessel TM. Principles of Neuroscience. New York, NY: McGraw-Hill; 2000
    Google Scholar
  • 29 Vidor DCGM. Aquisição lexical inicial por crianças falantes de português brasileiro: discussão do fenômeno da explosão do vocabulário e da atuação da hipótese do viés nominal [Tese Doutorado em Letras]. Instituto de Letras e Artes da PUCRS, Porto Alegre, Brasil; 2008
    Google Scholar
  • 30 Johnston MV, Hagberg H. Sex and the pathogenesis of cerebral palsy. Dev Med Child Neurol 2007; 49 (1) 74-78
    Google Scholar
  • 31 Kovas Y, Hayiou-Thomas ME, Oliver B, Dale PS, Bishop DV, Plomin R. Genetic influences in different aspects of language development: the etiology of language skills in 4.5-year-old twins. Child Dev 2005; 76 (3) 632-651
    CrossrefGoogle Scholar
  • 32 Bee HL, Mitchell SK, Barnard KE, Eyres SJ, Hammond MA. Predicting intellectual outcomes: Sex differences in response to early environmental stimulation. Sex Roles 1984; 10 (9–10) 783-803
    CrossrefGoogle Scholar