J Neurol Surg B Skull Base 2014; 75(05): 293-300
DOI: 10.1055/s-0033-1361837
Invited Review
Georg Thieme Verlag KG Stuttgart · New York

Anatomy and Cellular Constituents of the Human Olfactory Mucosa: A Review

C. Russell Chen
1   Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom
,
Carolina Kachramanoglou
1   Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom
,
Daqing Li
1   Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom
,
Peter Andrews
2   Department of ENT, Royal National Throat Nose and Ear Hospital, London, United Kingdom
,
David Choi
1   Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom
› Author Affiliations
Further Information

Publication History

11 August 2012

07 October 2013

Publication Date:
26 June 2014 (online)

Preview

Abstract

Studies using animal models have recently suggested that the olfactory mucosa may be a source of cells capable of stimulating and contributing to complex neurologic regeneration. Several groups have already transplanted cell derivatives from the olfactory mucosa into injury models, and the results so far have been promising. To fully appreciate the meaning of these experiments, a better understanding of the cellular biology and physiology of the olfactory system is necessary. It is therefore of utmost importance for us to first identify and understand its constituents.