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DOI: 10.1055/s-0033-1352251
Chemical composition and biological activities of extracts from an endemic Salvia cilicica Boiss.
The genus Salvia L. (Lamiaceae) comprises about 900 species around the world, while it is presented with 89 species and 93 taxons in Turkey, approximately half of which is endemic (1,2). Anatolia is the major gene center in Asia. The previous studies on this genus were about the isolation of their terpenic and flavonoid compounds and some biological activities. An endemic species in Adana-Pozanti, Salvia cilicica, has only a limited number of studies in the literature regarding its chemical composition and biological activity.
In our previous study, we presented the isolation of the terpenic compounds and the antileishmanial, antioxidant and cytotoxic activities of S. cilicica, which is endemic and is utilized in traditional medicine (3, 4). Because the successful study results of the biological activities of S. cilicica, further studies on the species other possible usages shall be conducted.
The present study concentrated on the compounds isolation and structure identifications (using spectroscopic methods 1H NMR, 13C NMR, HETCOR, COSY, NOESY, HSQC, HMBC, UV, IR, Mass) from the aerial parts and to determine the antimicrobial activity and preliminary studies on antiepileptic activity of the various extracts from the aerial parts and roots of S. cilicica.
Keywords: Salvia cilicica, isolation, antimicrobial activity, antiepileptic activity
References:
[1] Davis P.H. (Ed.). Flora of Turkey and the East Aegean Islands. Vol VII. Edinburgh: Edinburgh University Press, 1988.
[2] Davis P.H. (Ed.). Flora of Turkey and the East Aegean Islands. Vol X. Edinburgh: Edinburgh University Press, 1988.
[3] Tan N. et al. Abietane diterpenoids and triterpenoic acids from Salvia cilicica and their antileishmanial activities. Phytochemistry. 2002; 61: 881 – 884.
[4] Şen B., Yılmaz Özden T., Meriçli F., Meriçli A.H., Tan N., “Toros Dağları'nın Endemik Değeri Salvia cilicica Bitkisinin Aktivite Açısından Değerlendirilmesi”, XX.BİHAT 10 – 13 September 2012, Antalya – Turkey