Novel Sesquiterpenoid Glycosides and Sesquiterpenes from the Roots of Illicium henryi

Abstract

Seven new sesquiterpenoid glycosides, consisting of one thapsan-type (1), two capnellane-type (2 and 3), four floridanolide sesquiterpene glycosides (4–7), and one new azulene-type sesquiterpene (8), along with six known sesquiterpenes (9–14) were isolated from the roots of Illicium henryi. The structures of 1–8 were elucidated by extensive spectroscopic analyses and chemical methods. The absolute configurations of 1, 2, and 8 were determined based on Rh₂(OCOCF₃)₄-induced CD, Mo₂(OAc)₄-induced CD data, and calculated electronic circular dichroism (ECD), respectively. Compound 1 was found to exhibit weak neurotoxicant activity.

Key words

Illicium henryi - Illiciaceae - root - sesquiterpene - illihenlactoneoside A - neurotoxicant activity

• References

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