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Planta Med 2013; 79 - PN78
DOI: 10.1055/s-0033-1348759
DOI: 10.1055/s-0033-1348759
Pregnane Glycosides from the Root of Cynanchum otophyllum
Five new pregnane glycosides (1 – 5) were isolated from Cynanchum otophyllum Schneid, a folk medicinal plant known as Qingyangshen, endemic to the Yunnan Province of China.The structures were elucidated by NMR experiments. Compounds2 and 4 exhibited cytotoxic activity against HL-60 cells with IC50 values of 36 and 48µM, respectively.