Planta Med 2013; 79 - PN73
DOI: 10.1055/s-0033-1348754

Phenolic Glycosides and Sulfates from Dendrobium nobile

N Abe 1, Z Ali 1, IA Khan 1, 2
  • 1National Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS, 38677, USA
  • 2Department of Pharmacognosy, Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, MS, 38677, USA

The genus Dendrobium is an important plant in traditional Chinese medicine and is also known as 'Sekkoku' in Japanese Kampo medicine. D. nobile has been used as an analgesic and a tonic in China and Japan [1]. Alkaloids [2], bibenzyls [3], phenanthrens [4] and sesquiterpenoids [5] have been reported from this plant. Herein, we report the isolation of three new phenolic glycosides (1 – 3), two new phenolic sulfates, along with six known compounds. Their structures were elucidated through spectroscopic methods, including NMR experiments and MS spectra analyses.

Acknowledgements: The work was supported by the United States Food and Drug Administration (FDA) grant entitled “Science Based Authentication of Dietary Supplements” Number 5U01FD00 4246. References: [1] Bensky D (2004) Chinese Herbal Medicine: Materia Medica, 3 rd ed., p. 828 – 831. [2] Hedman K, et al. (1972) Acta. Chem. Scand., Vol. 26, p. 3177 – 3180. [3] Zhang X, et al. (2007) J. Nat. Prod., Vol. 70, p. 24 – 28. [4] Lee Y H, et al. (1995) Planta Med., Vol. 61, p. 178 – 180. [5] Ye Q, et al. (2002) Phytochem., Vol. 61, p. 885 – 890.