Endoscopy 2013; 45(09): 697-702
DOI: 10.1055/s-0033-1344395
Original article
© Georg Thieme Verlag KG Stuttgart · New York

A prospective cohort study evaluating a novel colonoscopy platform featuring full-spectrum endoscopy[*]

Ian Mark Gralnek
1  Department of Gastroenterology, Rambam Health Care Campus, Technion-Israel Institute of Technology, Haifa, Israel
3  Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel
,
Ori Segol
4  Lady Davis Carmel Medical Center, Haifa, Israel
,
Alain Suissa
1  Department of Gastroenterology, Rambam Health Care Campus, Technion-Israel Institute of Technology, Haifa, Israel
2  Gastrointestinal Endoscopy Unit, Elisha Hospital, Technion-Israel Institute of Technology, Haifa, Israel
,
Peter D. Siersema
5  Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, The Netherlands
,
David L. Carr-Locke
6  Beth Israel Medical Center, New York, New York, USA
,
Zamir Halpern
7  Department of Gastroenterology, Tel Aviv Sourasky Medical Center and Tel Aviv University School of Medicine, Tel Aviv, Israel
,
Erwin Santo
7  Department of Gastroenterology, Tel Aviv Sourasky Medical Center and Tel Aviv University School of Medicine, Tel Aviv, Israel
,
Svetlana Domanov
2  Gastrointestinal Endoscopy Unit, Elisha Hospital, Technion-Israel Institute of Technology, Haifa, Israel
› Author Affiliations
Further Information

Publication History

submitted 16 January 2013

accepted after revision 28 April 2013

Publication Date:
12 August 2013 (online)

Background and study aims: Although colonoscopy is the criterion standard for detecting colorectal adenomas and cancers, a significant percentage of adenomas are missed with this technique. We aimed to establish the feasibility, usability, and safety of a novel colonoscopy platform featuring full-spectrum endoscopy (FUSE).

Patients and methods: This was a prospective, single-center pilot and feasibility study. In total, 50 individuals, ages 18 – 70 years, underwent colonoscopy featuring FUSE (up to 330° field of view) for colorectal cancer screening, polyp surveillance, or diagnostic evaluation. Study end points included success of cecal intubation, time to cecal intubation, withdrawal time, total procedure time, success of therapeutic interventions, adverse events, and endoscopists’ subjective evaluation of FUSE.

Results: Cecal intubation was achieved in 50/50 individuals (100 %). Time to cecum (minutes, mean ± SD) was 3.1 ± 1.5 minutes, withdrawal time 12.7 ± 4.4 minutes, and total procedure time 15.3 ± 4.6 minutes. In 22/50 cases (44 %), 26 therapeutic interventions were performed: 19 (73.1 %) biopsies and 7 (26.9 %) polypectomies. No acute or delayed adverse events were observed. Patient satisfaction and endoscopist subjective evaluation were high.

Conclusions: A colonoscopy platform featuring full-spectrum endoscopy appears feasible, usable, and safe. These results represent an important advance in colonoscopy imaging technology and should be further pursued in comparative human studies.

* This material was presented in abstract form as an oral presentation (by I.M.G.) at United European Gastroenterology Week 2012 Free Paper Session “New endoscopic and imaging technologies,” 24 October 2012, Amsterdam, The Netherlands.