Zusammenfassung
Ziel der Studie war, die Assoziation von Zwangsmaßnahmen, erhoben mit der Staff Observation
Aggression Scale (SOAS-R) als Folge von Aggressivität mit pathologischen Kreatinkinasewerten
(CK-Werten) bei 317 akutpsychiatrischen Patienten zu untersuchen. In einer CHAID-Analyse
war ein pathologischer CK-Wert assoziiert mit der Durchführung von Zwangsmaßnahmen;
covariierende Variablen waren „Aggressionsanamnese“ und „Hauptdiagnose“. In der ROC-Analyse
zeigte sich für pathologische CK-Werte bezüglich späterer Durchführung von Zwangsmaßnahmen
eine Sensitivität von 73,5 % und eine Spezifität von 67,5 %.
Abstract
The aim of this study was to investigate the association of compulsory measures (CM)
with pathological Creatine Kinase (CK) levels in 317 patients admitted to a secure
psychiatric ward. The assumptions is that CK-activity is increased prior to administration
of CM because increases in CK-levels may represent aggressive behaviour as precursors
of a higher chance of administrating CM. The CK-levels were assessed immediately following
admission. During the course of the patients’ stay the frequency of different CM was
assessed by the use of the Staff Observation Aggression Scale. In a CHAID analysis
pathological CK-levels were associated with subsequent administration of CM. Lifetime
aggression and main diagnosis were associated with administration of CM as well. In
a ROC analysis concerning pathological CK-activity the AUC for subsequent administration
of CM was 70.5 % with a sensitivity of 73.5 % and a specifity of 67.5 %. Despite some
methodological shortcomings the study indicates that it could be useful to measure
CK-activity at the time of admission because pathological levels may indicate an increased
probability of administration of CM subsequent to aggressive behaviour.
Schlüsselwörter
Kreatinkinaseaktivität - Agitiertheit - Aggression - Zwangsmaßnahmen - Prädiktion
Keywords
creatine kinase activity - agitation - aggression - compulsory measures - prediction
