Lyme neuroborreliosis: aetiology and diagnosis of facial palsy in children from Tyrol

J Brunner; RW Reinhard; LB Zimmerhackl

doi:10.1055/s-0033-1337892

Neuropediatrics, Table of Contents

Lyme neuroborreliosis: aetiology and diagnosis of facial palsy in children from Tyrol

J Brunner ¹, RW Reinhard ², LB Zimmerhackl ¹

¹Department of Pediatrics, Medical University of Innsbruck, Austria
²Section of Hygiene and Medical Microbiology, Medical University of Innsbruck, Austria

Abstract

Background: Lyme neuroborreliosis (LNB) is the second most common manifestation of Borrelia burgdorferi sensu lato (s.l.) infection in Europe. LNB is difficult to differentiate from other etiologies of aseptic meningitis. Diagnostic criteria for LNB in children are not established. Therefore, based on the epidemiology of LNB in children from Tyrol, the aim of our study was to point out the necessity of a clear definition of pediatric LNB to avoid under diagnosis and overtreatment.

Patients and Methods: All medical charts of patients presented with acute peripheral facial palsy from January 2002 to December 2005 were reviewed. The patients were rediagnosed according to the criteria of the German Society of Neurology (DGN).

Results: We identified 66 patients with peripheral facial palsy. Thirty children were handled as B. burgdorferi s.l. infection. Five patients were over treated with antibiotic therapy. After reevaluation according to the DGN criteria 7 cases were reclassified as possible, 16 cases as probable and 7 cases as confirmed LNB.

Conclusions: Utilization of the established DGN criteria for pediatric LNB might help to elucidate the probability of LNB. Prospective studies are required to establish a classification system. A diagnostic tool, based on laboratory and clinical data, should avoid overtreatment of pediatric LNB.