Planta Med 2013; 79 - P33
DOI: 10.1055/s-0033-1336475

New Phenolic Compounds from Dendrobium 'Shi Hu'

N Abe 1, Z Ali 1, IA Khan 1, 2
  • 1National Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS, 38677, USA
  • 2Department of Pharmacognosy, Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, MS, 38677, USA

Dendrobium 'Shi Hu' is an important plant in traditional Chinese medicine and is also known as 'Sekkoku' in Japanese Kampo medicine. Although 'Shi Hu' can refer to several species within Dendrobium, the main species Dendrobium nobile is used as an analgesic and a tonic in China and Japan [1]. Alkaloids [2], bibenzyls [3], phenanthrenes [4], and sesquiterpenoids [5] have been isolated from this plant. We investigated new chemical constituents from this plant. Here we report the isolation of three new phenolic glycosides along with known compounds. Their structures were elucidated through extensive spectroscopic methods, including 1D and 2D NMR experiments and MS spectra analyses.

Acknowledgements: The work was supported by the United States Food and Drug Administration (FDA) grant entitled “Science Based Authentication of Dietary Supplements” Number 5U01FD004246. References: [1] Bensky D (2004) Chinese Herbal Medicine: Materia Medica, 3rd ed., p. 828 – 831. [2] Hedman K, Leander K. (1972) Acta Chem Scand, 26: 3177 – 3180. [3] Zhang X, Xu JK, et al. (2007)J Nat Prod, 70: 24 – 28. [4] Lee YH, Park JD, et al. (1995) Planta Med, 61: 178 – 180. [5] Ye Q, Qin G, Zhao W (2002) Phytochem, 61: 885 – 890.