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Horm Metab Res 2013; 45(07): 477-484
DOI: 10.1055/s-0033-1334945
Review
© Georg Thieme Verlag KG Stuttgart · New York

An Active Role for Steroid-binding Globulins: An Update

J. D. Caldwell
1   LECOM – Pharmacology, Erie, Pennsylvania, USA
,
G. F. Jirikowski
2   Department of Anatomy, University of Jena, Jena, Germany
› Author Affiliations
Further Information

Publication History

received 20 December 2012

accepted 05 February 2013

Publication Date:
02 April 2013 (online)

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Abstract

It has been 7 years (can it really be that long?) since we co-edited a volume (#38) of Hormone and Metabolic Research that focused on evidence that steroid-binding globulins play an active role in the actions of steroids. There has been considerable progress in identifying the location, the physiological actions, and of determining the role of binding globulins in the actions of steroids and identifying a membrane-associated receptor for a binding protein since then and this review will discuss this progress.

Key words

sex hormone-binding globulin - corticosteroid-binding globulin - vitamin D-binding globulin - RBP receptors - elastase nongenomic steroid effects
 

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