An evaluation of thickness effect in glycyrrihizic acid inside glycyrrhiza glabra root with compartion in several locations

Licorice is a self-propelling plant that has many applications in food, tobacco and pharmaceutical industries. Glycyrrhiza glabra is a kind of licorice whose main active constituents a triterpenoid saponin called glycyrrhizin. In this article we selected roots in three thickness sizes 0.4 to 1.5cm as s (small), 1.5 to 2.5cm as m (medium), 2.5 to 3.5cm as l (large) then roots were extracted with pressurized hot water extraction method inside Lab scale extractor (5 Liters) then evaporated and dried to analyze Glycyrrhizic acid content with HPLC.The results showed roots from all of locations are following this rule: more thickness, more Glycyrrhizic acid content such as in Afghanis, Uzbekistan, Turkey, Azerbaijan And Iran (7 areas) but we did not see similar slope for increasing glycyrrhizic acid against of thickness.